BIOTECHNOGY: PATHWAYS TO DISEASE PREVENTION AND THERAPY (BPDPT)

生物技术：疾病预防和治疗途径 (BPDPT)

• 批准号: 8357113
• 负责人: CARL B GOODMAN
• 金额: $ 32.77万
• 依托单位: FLORIDA AGRICULTURAL AND MECHANICAL UNIV
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357113
• 关键词: Biological Assay; Biomedical Research; Biotechnology; Collaborations; Core Facility; DNA Damage; DNA analysis; Development; Environment; Equipment; Faculty; Florida; Flow Cytometry; Fostering; Funding; Genomics; Goals; Grant; Mission; Molecular Biology; National Center for Research Resources; Pathway interactions; Pharmacologic Substance; Prevention therapy; Principal Investigator; Protein Analysis; Proteomics; RNA analysis; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Source; Technical Expertise; Technology; Time; Training; United States National Institutes of Health; Universities; Western Blotting; cost; disorder prevention; gel electrophoresis

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. ABSTRACT The Biotechnology: Pathways to Disease Prevention and Therapy (BPDPT) is an expansion of the previously funded molecular biology research activity. Its' continuing mission is to provide the university biomedical research investigators with contemporary molecular biology technology and technical expertise. This will strengthen the research infrastructure at Florida A&M University. The long-term goal of this effort is to establish informational and technical resources that will result in increased molecular biology expertise of the research faculty, continual investigator collaborations, and foster new biomedical research collaborative ventures. Development of the BPDPT will also increase new faculty recruitment opportunities at Florida A&M University. To complete these goals the following specific aims have been identified: 1) Establish the equipment infrastructure needed for molecular biology research; 2) Develop a University wide collaborative environment for biomedical research investigators; 3) Facilitate avenues by which faculty can receive molecular biology training; and 4) Increase the number of investigators involved in molecular biology research. Currently we have established traditional molecular biology technology including real-time PCR; western blot analysis; protein, DNA, & RNA analysis via gel electrophoresis; DNA damage analysis via the COMET assay, and flow cytometry. In the proposed activity we plan to expand the molecular biology expertise to include proteomics and genomics. Ultimately, we plan to expand the molecular biology research activity to a full functioning self-sustaining core facility. Overall, the BPDPT will serve to establish beneficial resources that will result in increased molecular biology expertise of the research faculty, continual investigator collaborations, and foster new biomedical research collaborative ventures and strengthens the research infrastructure at Florida A&M University. Supported by NIH/NCRR/RCMI G12RR03020.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 抽象的 生物技术：疾病预防和治疗途径（BPDPT）是先前资助的分子生物学研究活动的扩展。其持续使命是为大学生物医学研究人员提供当代分子生物学技术和技术专业知识。这将加强佛罗里达农工大学的研究基础设施。这项工作的长期目标是建立信息和技术资源，从而提高研究人员的分子生物学专业知识，持续的研究人员合作，并培育新的生物医学研究合作企业。 BPDPT 的发展还将增加佛罗里达农工大学新教师的招聘机会。为了完成这些目标，确定了以下具体目标： 1）建立分子生物学研究所需的设备基础设施； 2）为生物医学研究人员建立大学范围内的协作环境； 3) 为教师接受分子生物学培训提供便利； 4) 增加参与分子生物学研究的研究者数量。目前我们已经建立了包括实时PCR在内的传统分子生物学技术；蛋白质印迹分析；通过凝胶电泳进行蛋白质、DNA 和 RNA 分析；通过 COMET 测定和流式细胞术进行 DNA 损伤分析。在拟议的活动中，我们计划扩展分子生物学专业知识，包括蛋白质组学和基因组学。 最终，我们计划将分子生物学研究活动扩展到功能齐全、自我维持的核心设施。 总体而言，BPDPT 将有助于建立有益的资源，从而提高研究人员的分子生物学专业知识、持续的研究人员合作、培育新的生物医学研究合作企业并加强佛罗里达农工大学的研究基础设施。由 NIH/NCRR/RCMI G12RR03020 支持。