RELATIONSHIP OF METABOLIC ABNORMALITIES TO HEPATIC STEATOSIS IN HUMAN

人体代谢异常与肝脂肪变性的关系

• 批准号: 8166550
• 负责人: RICHARD K. STERLING
• 金额: $ 0.87万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166550
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Development; Dyslipidemias; Fatty Liver; Fibrosis; Funding; Grant; HIV; Highly Active Antiretroviral Therapy; Human; Institution; Insulin Resistance; Lipodystrophy; Metabolic; Patients; Research; Research Personnel; Resources; Source; Steatohepatitis; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Long term HAART use is associated with insulin resistance (IR) and dyslipidemia, which can result in the development of hepatic steatosis and progressive steatohepatitis and fibrosis. To determine the relationship of insulin resistance (IR), lipodystrophy (LD), and HAART use to hepatic steatosis/NASH in HIV infected patients.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 长期使用HAART与胰岛素抵抗（IR）和血脂异常相关，可导致肝脂肪变性和进行性脂肪性肝炎和纤维化的发展。 确定HIV感染患者中胰岛素抵抗（IR）、脂肪代谢障碍（LD）和HAART使用与肝脂肪变性/NASH的关系。