INCLUSION BODY MYOPATHY ASSOPCIATED WITH APAGET DISEASE OF BONE AND FRONTOTEMPOR

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，但不一定是研究者所在的机构。 包涵体肌病与佩吉特骨病和/或痴呆相关，是一种罕见的进行性常染色体显性遗传病。 在这项研究中，研究人员建议研究受试者是否具有这种遗传特征的知识如何影响他/她的焦虑和抑郁水平。 受试者将被问到他们是否愿意接受这种基因的测试，并将进行一系列问卷调查和量表测试，以测试焦虑和抑郁的水平。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Inclusion body myopathy associated with Paget s disease of the bone and/or dementia is a rare progressive autosomal dominant disorder. In this study the researchers propose to study how the knowledge of whether or not the subject has this genetic trait affects his/her levels of anxiety and depression. Subjects will be asked if they wish to be tested for this gene and a series of questionnaires and scales will be administered to test levels of anxiety and depression.