MITOCHONDRIAL DISEASES

线粒体疾病

• 批准号: 8166898
• 负责人: Douglas C Wallace
• 金额: $ 0.31万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166898
• 关键词: Animals; Bacteria; Cell physiology; Cells; Computer Retrieval of Information on Scientific Projects Database; Cytoplasm; Funding; Grant; Institution; Investigation; Life; Mitochondria; Mitochondrial Diseases; Nature; Organelles; Plants; Prevalence; Protocols documentation; Research; Research Personnel; Resources; Source; United States National Institutes of Health; progenitor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this research protocol is to continue my thirty year investigation of the nature and prevalence of mitochondrial disease. The mitochondria are organelles within the cytoplasm of our cells that produce most of the energy necessary for cellular function. The mitochondrial are in fact semi-autonomous bacteria living within our cells. These bacteria interred the progenitors of our cells as symbionts about three billion years ago, before multi-cellular plants and animals evolved. Today these mitochondria are an integral part of our cells without which we could not live.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 该研究方案的目的是继续我对线粒体疾病的性质和患病率的三十年调查。 线粒体是细胞细胞质内的细胞器，它们产生了细胞功能所需的大部分能量。 线粒体实际上是生活在我们细胞中的半自治细菌。 这些细菌将我们细胞的祖细胞埋在大约30亿年前，然后在多细胞动植物进化之前。 如今，这些线粒体是我们细胞不可或缺的一部分，没有我们无法生存。