COBRE: U OF KANSAS MEDICAL CTR: ANALYTICAL CORE

COBRE：堪萨斯大学医学中心 CTR：分析核心

• 批准号: 8167662
• 负责人: Gregory Allen Reed
• 金额: $ 10.58万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167662
• 关键词: Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Disease; Funding; Grant; Health; High Pressure Liquid Chromatography; Institution; Kansas; Medical; Performance; Preparation; Research; Research Personnel; Resources; Sampling; Source; Spectrophotometry; Training; United States National Institutes of Health; Work; analytical tool; fast protein liquid chromatography; instrument; instrumentation; liver function; programs; quality assurance

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Analytical Core will support the investigators of the COBRE projects by providing instrumentation and expertise in its application to research problems. Specifically, the Analytical Core will provide and promote HPLC, LC-MS/MS, FPLC, and multi-mode spectrophotometry as analytical tools available to our investigators. This Core will provide COBRE investigators with modern instrumental approaches for the isolation, identification, and quantification of compounds of relevance to their studies of liver function in health and disease. We will validate instrument performance as a component of an overall quality assurance program for this core facility. This Core will assist and train COBRE investigators in appropriate sampling and sample preparation to take advantage of these instrumental approaches. Finally, the Analytical Core will develop working relationships with other Core Facilities on this campus and on other campuses in the state to further develop the capabilities and the efficiency of all Cores.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 分析核心将通过在研究问题中提供仪器和专业知识来支持毛绒项目的调查人员。具体而言，分析核心将提供和促进HPLC，LC-MS/MS，FPLC和多模式分光光度计作为我们研究者可用的分析工具。该核心将为毛绒研究人员提供现代的工具方法，以隔离，鉴定和量化与其健康和疾病中肝功能研究相关的化合物。我们将验证仪器性能，作为该核心设施总体质量保证计划的组成部分。 该核心将协助和训练毛绒研究人员进行适当的抽样和样品准备，以利用这些工具方法。最后，分析核心将与该校园和该州其他校园的其他核心设施建立工作关系，以进一步发展所有核心的能力和效率。