COBRE: U OF KANSAS MEDICAL CTR: CENTER JOINT PROJECTS

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 我们召开了多次会议来决定我们可能开发成计划项目的主题。 由于代谢综合征是一个主要的公共卫生问题，而 NASH（非酒精性脂肪肝炎）是该综合征的一个组成部分，因此我们决定研究可能导致这一现象的因素。 因此，我们设计了四个实验来研究小鼠的昼夜节律、各种遗传背景（品系）、各种饮食和年龄（老）。 我们收集了其中三个实验的组织。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We had a number of meetings to decide topics that we might develop into program projects. Because the metabolic syndrome is a major public health problem, and NASH (non-alcoholic steahepatitis) is a component of this syndrome, we decided to examine factors that might contribute to this phenomenon. Therefore, we have designed four experiments to investigate the circadian rhythm, various genetic backgrounds (strains), various diets, and ages (old) of mice. We have collected the tissues of three of these experiments.