CORE F CENTER JOINT PROJECTS

核心 F 中心联合项目

• 批准号: 7959510
• 负责人: CURTIS DEAN KLAASSEN
• 金额: $ 27.1万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959510
• 关键词: Age; Circadian Rhythms; Computer Retrieval of Information on Scientific Projects Database; Diet; Disease; Funding; Genetic; Grant; Health; Institution; Joints; Liver; Metabolic syndrome; Mus; Nuclear Receptors; Public Health; Research; Research Personnel; Resources; Source; Syndrome; Time; Tissues; United States National Institutes of Health; design; meetings; non-alcoholic; programs; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have spent a considerable amount of time this last year planning joint projects that we hope will evolve into one or more program projects. We started out by having meetings to decide topics that we might develop into program projects. Because the metabolic syndrome is a major public health problem, and NASH (non-alcoholic steahepatitis) is a component of this syndrome, we decided to examine factors that might contribute to this phenomenon. Therefore, we have designed four experiments to investigate the circadian rhythm, various genetic backgrounds (strains), various diets, and ages (old) of mice. We have collected the tissues of three of these experiments.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 去年，我们花了大量的时间来规划联合项目，我们希望这些项目能够发展成一个或多个项目。 一开始，我们召开会议来决定我们可能发展成项目的主题。 由于代谢综合征是一个主要的公共卫生问题，NASH（非酒精性脂肪性肝炎）是这种综合征的一个组成部分，我们决定检查可能导致这种现象的因素。 因此，我们设计了四个实验来研究小鼠的昼夜节律、各种遗传背景（品系）、各种饮食和年龄（老年）。 我们收集了其中三个实验的组织。