REGULATING SYNAPTIC VESICLE EXOCYTOSIS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这个项目的长期目标是确定和描述机械的特征， 突触前蛋白介导神经递质的释放，以期提供 了解这些神经机制如何在许多神经疾病中发生扭曲的基本信息。 特定目标 本提案的目的是研究VSM1(v-SNARE主机)的功能 蛋白1)在突触终末。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The long-term goal of this project is to identify and characterize the machinery by which presynaptic proteins mediate neurotransmitter release, with a view towards providing fundamental information for understanding of how these neural mechanisms might become distorted in many neurological disorders. Specific Aim The objective of this proposal is to investigate the function of VSM1 (v-SNARE master protein 1) in synaptic terminals.