REGULATING SYNAPTIC VESICLE EXOCYTOSIS

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 中心，但不一定是研究者所在的机构。 该项目的长期目标是确定和描述 突触前蛋白介导神经递质释放，目的是提供 了解这些神经机制如何在许多神经系统疾病中被扭曲的基本信息。 具体目标 本提案的目的是研究VSM 1（v-SNARE主机）的功能 蛋白1）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The long-term goal of this project is to identify and characterize the machinery by which presynaptic proteins mediate neurotransmitter release, with a view towards providing fundamental information for understanding of how these neural mechanisms might become distorted in many neurological disorders. Specific Aim The objective of this proposal is to investigate the function of VSM1 (v-SNARE master protein 1) in synaptic terminals.