Advancing Competitive Biomedical Research in Puerto Rico

推进波多黎各有竞争力的生物医学研究

• 批准号: 7877795
• 负责人: SANDRA PENA DE ORTIZ
• 金额: $ 351.81万
• 依托单位: UNIVERSITY OF PUERTO RICO
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-15 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7877795
• 关键词: Active Sites; Address; Advisory Committees; Affect; Area; Award; Binding; Bioinformatics; Biological; Biomedical Research; Bioreactors; Cell Wall; Cell membrane; Centers of Research Excellence; Chemicals; Collaborations; Competence; Complement; Complex; Consult; Continuing Education; Cyclodextrins; Cytoskeleton; Dehydration; Development; Digit structure; Disease; Drug Design; Education; Educational workshop; Electron Spin Resonance Spectroscopy; Electronics; Energy Transfer; Ensure; Environment; Enzyme Stability; Enzymes; Ethylene Glycols; Etiology; Evaluation; Exhibits; Exposure to; Faculty; Fluorine; Fostering; Freeze Drying; Gene Expression; Genes; Goals; Grant; Growth; Hela Cells; Hour; Human Resources; Hydration status; Hydrolase; Immobilization; Immobilized Enzymes; Institution; Internships; Intervention; Island; Kentucky; Liquid substance; Long-Term Effects; Malignant Neoplasms; Measures; Mechanics; Medical; Membrane; Mentors; Metals; Methodology; Methods; Modification; Molecular; Molecular Medicine; Movement; National Center for Research Resources; Neurosciences; Nuclear Magnetic Resonance; Nucleic Acids; Organic solvent product; Performance; Pharmacologic Substance; Plasma; Process; Productivity; Protein Dynamics; Published Comment; Puerto Rico; RNA; RNA Stability; Reaction; Research; Research Infrastructure; Research Project Grants; Role; Science; Series; Services; Solutions; Solvents; Spin Labels; Structure; Students; Surface; Technical Expertise; Techniques; Technology; Technology Transfer; Theoretical Studies; Time; Virus Diseases; Water; Work; aqueous; base; career; catalyst; design; enzyme activity; ethylene glycol; flexibility; improved; insight; instrumentation; interest; knowledge base; macromolecule; molecular dynamics; nucleic acid stability; programs; public health relevance; quantum; research study; simulation

DESCRIPTION (provided by applicant): This renewal of PRAABRE represents a step forward in our efforts to foster the continued development of the biomedical research infrastructure in Puerto Rico. Such continued development is achieved through the implementation of a strengthened and cohesive structure with improved integration of common scientific and educational interests, collaborations, and a newly created Mentoring Initiative. The structure of PRAABRE is represented in the following components: Administrative, Bioinformatics, Scientific Network, Centralize Research and Instrumentation, and Science and Technology and Education. The Administrative Core provides the programmatic direction for the entire PRAABRE. The new Mentoring Initiative will standardize mentoring practices among participating Institutions at all levels of intervention, from undergraduate student research to mentored research at the faculty level. This initiative will also coordinate Grantsmanship Workshops offered by Kentucky INBRE personnel on a yearly basis. The Administrative Core, via a close interaction with the External Advisory Committee and an External Independent Evaluator, will also organize the overall formative and additive evaluation process of PRAABRE. The Bioinformatics Core will assertively foster and stimulate the development of bioinformatics research, collaborations, and consulting services. This core will also be responsible for maintaining high performance lnternet-2 network capabilities at participating Institutions. Our initiative for providing Access to biomedical Research Electronic Information will also be coordinated by the Bioinformatics Core. The Scientific Network will host 11 INBRE sponsored research projects in PRAABRE, all organized into thrust areas within the biomedical sciences. The Centralized Research and Instrumentation Core integrates the corresponding facilities established at the UPR-Rio Piedras and Medical Sciences Campuses by prior BRIN and INBRE cycles, as well as by COBRE and RCMI, all NCRR programs. The Science and Technology Competence and Education Core will host the PRAABRE Seminar Series, Technology Transfer Awards, Faculty Summer Internships, Continued Education and Technology Competence Workshops, and the Science-on-Wheels project, a K-12 initiative. This PRAABRE Core will also help coordinate Summer Internships in Kentucky for PRAABRE students, an Initiative covered by the Kentucky INBRE. A special quality of this renewal application is the collaborations among the distinct cores, which makes the proposed efforts a true networking of ideas, education, and biomedical research in the Island of Puerto Rico. PUBLIC HEALTH RELEVANCE (provided by applicant): This renewal application will further augment and strengthen Puerto Rico's biomedical research capacity, productivity, and competitiveness. PRAABRE will continue to build upon the established biomedical research network of 16 Institutions with a scientific focus on Neuroscience, Molecular Medicine, and Drug Design. PRAABRE will also serve as a pipeline for students throughout the development of their scientific careers and contribute to the development of a knowledge-based economy in the Island.

描述（由申请人提供）：PRAABRE的这一更新代表了我们在努力促进波多黎各生物医学研究基础设施的持续发展方面向前迈出的一步。这种持续发展是通过实施一个加强和凝聚力的结构，改善共同的科学和教育利益，合作和新创建的指导倡议的整合来实现的。PRAABRE的结构由以下部分组成：行政、生物信息学、科学网络、集中研究和仪器以及科学技术和教育。行政核心为整个PRAABRE提供方案指导。新的指导倡议将使参与机构在所有干预级别的指导做法标准化，从本科生研究到教师一级的指导研究。该倡议还将协调肯塔基州INBRE人员每年举办的格兰披治研讨会。行政核心还将通过与外部咨询委员会和外部独立评估员的密切互动，组织对PRAABRE的总体形成性和附加性评估进程。生物信息学核心将积极促进和刺激生物信息学研究，合作和咨询服务的发展。 这个核心亦会负责维持参与院校的高效能第二代互联网网络功能。我们提供生物医学研究电子信息的倡议也将由生物信息学核心协调。科学网络将在PRAABRE主持11个INBRE赞助的研究项目，所有这些项目都被组织到生物医学科学的重点领域。集中研究和仪器核心集成了在UPR里约Piedras和医学科学校园由以前的BRIN和INBRE周期，以及COBRE和RCMI，所有NCRR计划建立的相应设施。科学和技术能力和教育核心将主办PRAABRE研讨会系列，技术转让奖，教师暑期实习，继续教育和技术能力研讨会，以及车轮上的科学项目，一个K-12倡议。 这个PRAABRE核心还将帮助协调PRAABRE学生在肯塔基州的暑期实习，这是肯塔基州INBRE所涵盖的一项倡议。这一更新申请的一个特殊性质是不同核心之间的合作，这使得拟议的努力成为波多黎各岛思想、教育和生物医学研究的真正网络。 公共卫生相关性（由申请人提供）：此更新申请将进一步扩大和加强波多黎各的生物医学研究能力，生产力和竞争力。PRAABRE将继续建立在已建立的16个机构的生物医学研究网络的基础上，科学重点是神经科学，分子医学和药物设计。PRAABRE还将作为学生在科学事业发展过程中的一个渠道，并为该岛知识型经济的发展做出贡献。