CENTRALIZED RESEARCH INSTRUMENTATION CORE

集中研究仪器核心

• 批准号: 8360146
• 负责人: SANDRA PENA DE ORTIZ
• 金额: $ 14.17万
• 依托单位: UNIVERSITY OF PUERTO RICO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360146
• 关键词: Academia; Area; Biomedical Research; Clinical; Collaborations; Competence; Consult; Core Facility; Development; Educational workshop; Environment; Fostering; Funding; Genetic; Genomics; Genotype; Goals; Grant; Human; Industry; Institution; Island; Manuscripts; Medical; Mentors; Mentorship; National Center for Research Resources; Piedra; Preparation; Principal Investigator; Productivity; Proteins; Proteomics; Puerto Rico; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Running; Science; Scientist; Services; Source; Students; Technology; Time; Training; United States National Institutes of Health; Universities; Validation; Work; X-Ray Crystallography; career; career development; cost; empowered; experience; functional genomics; instrument; instrumentation; investigator training; meetings; member; new technology; programs; research and development; research study; technology development

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Centralized Research and Instrumentation Core: The BioMolecular Sciences Network (BMSN). The BMSN embodies the integration of the principal BioMolecular Sciences Resources (BMSRs) in Puerto Rico as part of the research and career development objectives of the Puerto Rico Alliance for the Advancement of Biomedical Research Excellence (PRAABRE). Our overall goal in the BMSN is to work in a concerted fashion, by providing mentorship and scientific support, leading to the empowering of PRAABRE-supported investigators and students from primarily undergraduate institutions (PUIs) in the Island. We envision that fostering a concerted, integrated, and collaborative environment in Puerto Rico catalyzed by the BMSN will i) contribute to the expansion of scientific competence among researchers and students at PUIs and ii) help create productive partnerships between these investigators (including their mentors and collaborators) and those directing active research endeavors and instrumentation facilities (the Core Facility Coordinators) within the two main PRAABRE mentoring institutions in the Island: the Rio Piedras and Medical Sciences Campuses of the University of Puerto Rico (UPR-RP and UPR-MSC), respectively. These goals will be achieved by the integration of researchers in the two major areas of the BMSN: genomics and proteomics. The integration of resources and scientific expertise available at the BMSN will empower researchers and augment their scientific competence, resulting in a better use of BMSRs and enhanced competitiveness. In addition, the proposed activities will result in more active networking among existing instrumentation facilities and BMSN scientists, thus impacting the collaborative, consulting, training, and service capabilities for all members of PRAABRE. Specific Aim 1: Integration of existing Instrumentation Facilities. Six facilities dedicated to genomics and proteomics research, including new technology development constitute the BMSN. The specialized areas represented by the BMSN are Functional Genomics, Genomics and Genotyping, Human and Clinical Genetics, Proteomics, and Protein X-Ray Crystallography. The BMSN Director, Dr. Sandra Pena de Ortiz, together with the Genomics and Proteomics Area Leaders (Drs. Tomas Hrbek and Irving Vega, respectively), will oversee the integration and collaboration activities proposed to provide scientific exchange and expertise among Core Facility Coordinators and PRAABRE-supported investigators, at the same time maximizing the use and development of BMSRs in Puerto Rico. Specific Aim 2: Competence Enhancement: Empowering PUI's investigators, students and research staff in the fields represented and developed at the BMSN. The utilization of the technology available will be maximized when researchers are capacitated to understand how these instruments and technologies may impact their research. The Core Facility Coordinators will continue to develop productive collaborations between the academia and industry by offering and developing new Thematic Workshops to train investigators, students and research staff at PUI's and industry in Puerto Rico. The workshops will consist of theoretical and hands-on experiences. The development and execution of this specific aim will not only contribute to the increased usage of instrumentation facilities within the BMSN, but more importantly, empower researchers in Puerto Rico, especially those at PUIs to implement new biomolecular approaches and resources to their research projects with the goal of enhancing competitiveness, productivity, and scientific impact. Specific Aim 3: Provide scientific support to the PRAABRE supported investigators at PUIs and to the overall scientific network in the Island. The development of new investigators mainly at PUIs is one of the objectives of the PRAABRE program. The BMSN will foster the scientific development of investigators funded through this program by providing mentorship, guidance and scientific support. The projects that are part of the PRAABRE Research Core will benefit from the technology and expertise available at the BMSN. The Core Facility Coordinators will encourage one-on-one meetings for experiment planning, validation strategies and manuscript preparation. This support will enhance the productivity and, consequently, competitiveness of PUIs investigators. This aim will run concurrently with the above mentioned Competence Enhancement component. In general, the BMSN will foster the development of research projects and directly impact the research careers of investigator at PUIs and other academic institutions in Puerto Rico.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 集中研究和仪器核心：生物分子科学网络（BMSN）。 BMSN体现了波多黎各的主要生物分子科学资源（BMSRS），这是波多黎各卓越发展卓越生物医学研究（PRAABRE）的研究和职业发展目标的一部分。我们在BMSN中的总体目标是通过提供指导和科学支持，以一致的方式工作，从而赋予Praabre支持的调查人员和主要来自本科机构（PUI）的学生的能力。我们设想 BMSN促进波多黎各的一致，整合和协作的环境，i）有助于在PUIS和II的研究人员和学生之间扩大科学能力，以帮助这些研究人员（包括他们的导师和协作者）之间建立富有成效的伙伴关系（包括主动研究人员），并在积极的研究方面进行了核心设施（核心设施）（两者都在核心设施）（两者核心设施）（包括核心设施），以实现核心设施（包括核心设施），以实现核心设施（包括核心设施），以实现核心设施（包括核心设施），以实现核心设施（岛：里约皮埃拉斯和医学科学校园 波多黎各大学（UPR-RP和UPR-MSC）分别是。这些目标将通过在BMSN的两个主要领域的研究人员组成：基因组学和蛋白质组学。 BMSN提供的资源和科学专业知识的整合将增强研究人员的能力并增强其科学能力，从而更好地利用BMSR并增强竞争力。此外，拟议的活动将导致现有仪器设施和BMSN科学家之间的更积极的网络， 从而影响了Praabre所有成员的协作，咨询，培训和服务能力。 特定目的1：现有仪器设施的整合。包括新技术开发在内的六个专门针对基因组学和蛋白质组学研究的设施构成了BMSN。 BMSN代表的专业领域是功能基因组学，基因组学和基因分型，人类和临床 遗传学，蛋白质组学和蛋白质X射线晶体学。 BMSN主任Sandra Pena de Ortiz博士以及基因组学和蛋白质组学领域的领导者（分别是Tomas Hrbek博士和Irving Vega博士）将监督旨在在同一时间内使用核心设施协调员和Praabre ppraabre ppraabre pprabrede的研究者之间的核心设施协调员和Prabre conders的核心交流和专业知识，并在Maximimize in Demimims Inspreation和Prabimizimize and and and Inspeation和Septrectors中的使用和协作活动。 特定目的2：增强能力：授权PUI的调查人员，学生和研究人员在BMSN代表和开发。当研究人员被电容以了解这些工具和技术如何影响其研究时，可用技术的利用将被最大化。核心设施协调员将继续发展生产力 学术界和行业之间的合作是通过提供和开发新的主题研讨会来培训波多黎各PUI和工业的研究人员，学生和研究人员。研讨会将包括理论和动手经验。这个特定目标的发展和执行不会 仅有助于增加BMSN内部仪器设施的使用，但更重要的是，赋予波多黎各的研究人员，尤其是PUI的研究人员，尤其是那些在PUIS上实施新的生物分子方法和资源，以增强竞争力，生产力和科学的目的 影响。 特定目的3：为PUI的Praabre支持的研究人员和岛上整个科学网络提供科学支持。主要在PUI的新调查人员的发展是Praabre计划的目标之一。 BMSN将通过提供指导，指导和科学支持来促进通过该计划资助的研究人员的科学发展。属于Praabre研究核心的项目将受益于BMSN的技术和专业知识。核心设施协调员将鼓励一对一的会议进行实验计划，验证策略和手稿准备。这种支持将提高生产率，因此 PUIS研究者的竞争力。该目标将与上述能力增强组件同时运行。通常，BMSN将促进研究项目的发展，并直接影响PUIS和波多黎各的其他学术机构的研究人员。