CENTER FOR VISUAL AND COGNITIVE NEUROSCIENCE

视觉和认知神经科学中心

• 批准号: 8168448
• 负责人: MARK E. McCourt
• 金额: $ 212.63万
• 依托单位: NORTH DAKOTA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-25 至 2011-08-24
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168448
• 关键词: Advisory Committees; Agnosia; Amblyopia; Arts; Attention; Attention deficit hyperactivity disorder; Autistic Disorder; Behavior; Centers of Research Excellence; Cognition; Cognitive; Commit; Computer Retrieval of Information on Scientific Projects Database; Computers; Dementia; Disease; Dyslexia; Electroencephalography; Emotions; Faculty; Funding; Future; Grant; Impaired cognition; Institution; Knowledge; Laboratories; Laboratory Technicians; Maintenance; Measures; Mental Depression; Mentors; Monoclonal Antibody R24; Multiple Sclerosis; Nervous System Physiology; Parkinson Disease; Perceptual Disorders; Pilot Projects; Post-Traumatic Stress Disorders; Postdoctoral Fellow; Prevalence; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Schizophrenia; Sensory; Source; Structure; Syndrome; Talents; Time; Training; United States National Institutes of Health; Visual; Visual Perception; Visual attention; age related; cognitive neuroscience; density; executive function; graduate student; infrastructure development; laboratory facility; member; neuroimaging; neuromechanism; normal aging; public health relevance; success; translational neuroscience; visual cognition

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): We propose renewal of our COBRE at NDSU. Our research focus is Visual and Cognitive Neuroscience. We describe four thematically interrelated primary projects directed by promising junior and senior investigators, which examine the neural mechanisms and functional significance of visual perception, visual attention, visual cognition and action. Our Specific Aims are: SPECIFIC AIM #1: To develop successful, independent, self-sustaining research projects for COBRE Project Directors to enable future success in obtaining R01 funding. This aim will be accomplished by obtaining COBRE support for thematically articulated research projects and by establishing an Administrative Core consisting of the PI/PD, a two-member Internal Advisory Committee, a three-member External Advisory Committee, as well as a group of five Project Mentors. SPECIFIC AIM #2: To enhance research infrastructure at NDSU through maintenance of multiuser Core laboratory facilities. The projects of the COBRE utilize state-of-the-art EEG neuroimaging to measure relationships between the structure and function of the nervous system and the behavior it governs. We will continue to enhance research infrastructure by supporting the Core laboratory for High-Density EEG, staffed by a full-time EEG laboratory technician and two full-time computer programmers. SPECIFIC AIM #3: To expand NDSU's research capability in visual and cognitive neuroscience by recruiting an additional faculty member with research expertise in translational neuroscience. We propose to recruit a visual or cognitive neuroscientist during the first year of the COBRE project. This new recruit will augment our critical mass of research talent that will sustain the Center beyond the initial years of COBRE support. This newly recruited faculty member will be eligible for CVCN support through a Pilot Project mechanism. SPECIFIC AIM #4: To establish a nationally recognized Center for Visual and Cognitive Neuroscience at NDSU. The realization of Specific Aims 1-3 will create a center of research excellence at NDSU which is guaranteed to attract additional quality faculty, postdoctoral fellows and graduate students committed to cutting-edge research in visual and cognitive neuroscience. The NDSU Center for Visual and Cognitive Neuroscience will be competitive for Institutional Training Grants (T32), Research Project Grants (ROI), and Infrastructure Development Grants (R24) which will sustain the Center beyond the initial years of support. PUBLIC HEALTH RELEVANCE (provided by applicant): Disordered perception, cognition, emotion, attention and executive function are hallmarks of debilitating and costly disease syndromes (ADHD, ARMD, agnosia, amblyopia, autism, depression, dementia, dyslexia, hemineglect, multiple sclerosis, Parkinson's disease, PTSD, and schizophrenia). Equally significant is the prevalence of such disorders in normal age-related sensory and cognitive decline. This COBRE is dedicated to the discovery of knowledge that illuminates and potentially ameliorates these conditions.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 描述（由申请人提供）：我们建议在NDSU更新我们的COBRE。我们的研究重点是视觉和认知神经科学。我们描述了四个主题相互关联的主要项目，由有前途的初级和高级研究人员指导，研究视觉感知，视觉注意，视觉认知和行动的神经机制和功能意义。我们的具体目标是： 具体目标1：为COBRE项目主任开发成功的，独立的，自我维持的研究项目，以确保未来成功获得R 01资金。这一目标将通过以下方式实现：获得COBRE对主题明确的研究项目的支持，并建立一个由PI/PD、两名成员的内部咨询委员会、三名成员的外部咨询委员会以及五名项目导师组成的行政核心。 具体目标#2：通过维护多用户核心实验室设施，加强NDSU的研究基础设施。COBRE的项目利用最先进的EEG神经成像技术来测量神经系统的结构和功能与其控制的行为之间的关系。我们将继续加强研究基础设施，支持高密度脑电图核心实验室，配备一名全职脑电图实验室技术员和两名全职计算机程序员。 具体目标3：通过招聘一名具有转化神经科学研究专长的教师，扩大NDSU在视觉和认知神经科学方面的研究能力。我们建议在COBRE项目的第一年招募一名视觉或认知神经科学家。这名新成员将增加我们的研究人才的临界质量，这将使该中心在COBRE支持的最初几年之后得以维持。这名新招聘的教师将有资格通过试点项目机制获得CVCN的支持。 具体目标#4：在NDSU建立一个国家认可的视觉和认知神经科学中心。具体目标1-3的实现将在NDSU创建一个卓越的研究中心，保证吸引更多的优质教师，博士后研究员和研究生致力于视觉和认知神经科学的前沿研究。NDSU视觉和认知神经科学中心将在机构培训赠款（T32），研究项目赠款（ROI）和基础设施开发赠款（R24）方面具有竞争力，这些赠款将使中心在最初的支持年之后继续发展。 公共卫生相关性（由申请人提供）：感知、认知、情感、注意力和执行功能障碍是使人衰弱和代价高昂的疾病综合征（ADHD、ARMD、失认症、弱视、自闭症、抑郁症、痴呆、阅读障碍、偏侧运动障碍、多发性硬化症、帕金森病、创伤后应激障碍和精神分裂症）的标志。同样重要的是，在正常的与年龄相关的感觉和认知能力下降中，这种疾病的患病率也很高。这个COBRE致力于发现知识，照亮并可能改善这些条件。