Immonology Core

贝勒-休斯顿CFAR免疫核心旨在提供最先进的流式细胞术能力、非流式细胞术免疫分析专业知识以及CFAR成员所需的技术培训。一个主要目标是支持高优先级CFAR倡议的研究，这些倡议促进机会领域的跨学科研究。该中心由两个独立但相互补充的实验室组成，一个是细胞学实验室(位于贝勒医学院)，另一个是临床免疫学实验室(位于德克萨斯大学休斯顿医学院)。常规的流式细胞术和细胞分类是在细胞学实验室以较低的成本为CFAR成员进行的。临床免疫学实验室提供其他免疫学服务，包括开发和表征新的分析方法，如用于测量生物标志物的ELISAT和ELISPOT分析。非常成功的免疫学核心由多萝西·E·刘易斯博士执导，他拥有30多年的流动和免疫学经验，在汇集跨学科研究人员方面有着出色的记录。贝勒的CFAR细胞学实验室由Joel Sederstrom管理，休斯顿大学的CFAR临床免疫学实验室由Jacob Couturier管理。核心由一个监督委员会监督。CORE未来将追求的机会领域包括发展BSL2细胞分选能力，开发免疫分析，以及提供免疫学方法的高级培训。核心主任负责核心实验室的日常运作；以标准化的方式规定使用的优先次序；适当时实行收费制度。在我们之前的资助期间，这一核心得到了高度的利用和赞赏，预计贝勒和休斯顿大学的调查人员将从其扩大的服务中受益。它的支持对于贝勒-UT休斯顿CFAR的持续成功至关重要。

The Baylor-UTHouston CFAR Immunology Core is designed to provide state-of-the-art flow cytometric capabilities, expertise for non-flow cytometry immunological assays, and technical training desired by members of the CFAR. A major goal Is to support research of high-priority CFAR initiatives that foster interdisciplinary research in areas of opportunity. The Core is organized into two separate but complementary laboratories, the Cytometry Laboratory (located at Baylor College of Medicine) and the Clinical Immunology Laboratory (located at UTHouston Medical School). Routine flow cytometry and cell sorting is conducted at reduced cost to CFAR members at the Cytometry Laboratory. The Clinical Immunology Laboratory provides other immunology services, including development and characterization of new assays such as ELISA and ELISPOT assays to measure biomarkers. The highly successful Immunology Core is directed by Dr. Dorothy E. Lewis, who has over 30 years of flow and immunologic experience and an outstanding track-record of bringing together interdisciplinary investigators. The CFAR Cytometry Laboratory at Baylor is managed by Joel Sederstrom, and the CFAR Clinical Immunology Laboratory at UTHouston by Jacob Couturier. The Core is supervised by an Oversight Committee. Future opportunity areas to be pursued by the Core include development of BSL2+ cell sorting capability, development of immune assays, and provision of advanced training in immunological methods. The Core Director has responsibility for day-to-day running of the Core laboratories; priorities for usage are prescribed in a standardized manner; a charge-back system is implemented where appropriate. This Core has been highly utilized and appreciated in our previous funding periods and it is anticipated that investigators at Baylor and UTHouston will benefit from its expanded services. Its support is essential for the continued success of the Baylor-UTHouston CFAR.