Clinical Core

核心F 杜克大学CFAR临床核心（核心F）为杜克大学CFAR内的HIV相关临床研究提供了一个动态的、高度积极的和有效的环境。根据CFAR的总体使命，该核心通过提供临床研究专业知识、监管支持、患者标本获取和社区参与，提供“增值”，以促进以患者为导向的研究。核心对杜克内部调查人员的需求做出了回应，并积极寻求机会， 扩大在达勒姆和国际研究中心的临床机会。该核心有三个具体目标：1）通过开发新的核心服务来促进临床和实验室研究者进行以患者为导向的前沿研究，这些服务应满足研究者的需求和CFAR的优先事项，例如国际合作，以及与标本库相关联的增强型数据库; 2）促进杜克大学CFAR研究人员之间以患者为导向的研究合作，特别是在艾滋病毒发病机制和艾滋病相关恶性肿瘤的CFAR优先领域，通过将杜克CFAR研究者的假设转化为临床研究，将新的临床观察带回实验室研究者，促进和领导跨学科研究团队，并积极参与CFAR会议和研讨会; 3）通过强调跨学科研究努力，吸引新的研究人员参与艾滋病毒/艾滋病的面向患者的研究，与杜克全球健康研究所和杜克综合癌症研究所等主要合作伙伴进行沟通，提出新的合作建议，并招募新的杜克教师。前四年的临床核心成就表明，临床核心将在下一个资助周期中作为CFAR内以患者为导向的研究的核心而蓬勃发展，推动CFAR实现其科学优先事项。

Core F The Duke University CFAR Clinical Core (Core F) provides a dynamic, higlily motivated and effective environment for HIV-related clinical studies within the Duke CFAR. In line with the overall mission for a CFAR, this Core provides "value-added" to facilitate patient-oriented research by providing clinical research expertise, regulatory support, access to patient specimens, and community involvement. The Core is responsive to the needs of the investigators within Duke and has aggressively pursued opportunities to expand clinical opportunities in Durham and through international sites. This Core has three specific aims: 1) To facilitate cutting edge patient-oriented research by clinical and laboratory investigators through the development of new Core services responsive to investigator needs and CFAR priorities such as international collaborations, and an enhanced database linked to a specimen repository; 2) To catalyze patient-oriented research collaborations between Duke CFAR investigators, especially within CFAR priority areas of HIV pathogenesis and AIDS-associated malignancies, by translating the hypotheses of Duke CFAR investigators into clinical studies, bringing novel clinical observations back to laboratory investigators, facilitating and leading interdisciplinary research teams, and actively participating in CFAR conferences and symposia; 3) To attract new investigators into patient-oriented research investigating HIV/AIDS by emphasizing interdisciplinary research efforts, communicating with key partners such as the Duke Global Health Institute and the Duke Comprehensive Cancer Institute, suggesting new collaborations, and recruiting new Duke faculty. Clinical Core accomplishments from the first four years suggest that the Clinical Core will thrive as the centerpiece of patient-oriented research within the CFAR in the next funding cycle, driving the CFAR to realize its scientific priorities.