STRUCTURE OF THE KIT RECEPTOR TYROSINE KINASE

试剂盒受体酪氨酸激酶的结构

• 批准号: 8169690
• 负责人: VINZENZ UNGER
• 金额: $ 1.29万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169690
• 关键词: Cell physiology; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Mediating; Membrane; Membrane Proteins; Receptor Protein-Tyrosine Kinases; Research; Research Personnel; Resources; Signal Transduction; Source; Structure; United States National Institutes of Health; receptor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Receptor Tyrosine Kinases (RTKs) are large single span membrane proteins that mediate many important cellular functions. While much progress has been made in the understanding of the soluble domains of the receptors, a picture of the whole receptor, including the membrane spanning helix. This lack in information is limiting for a full mechanstic understanding of the signal transduction mechanism(s) of this important class of membrane proteins.

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