XAS CHARACTERIZATION OF HIGH-VALENT IRON DIMERS RELEVANT TO METHANE MONOOXGENASE
与甲烷一氧化酶相关的高价铁二聚体的 XAS 表征
基本信息
- 批准号:8170198
- 负责人:
- 金额:$ 0.03万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-05-01 至 2011-02-28
- 项目状态:已结题
- 来源:
- 关键词:ComplexComputer Retrieval of Information on Scientific Projects DatabaseElectronsFundingGenerationsGrantHydrogen BondingInstitutionInvestigationIonsIronLigandsMetalsMethaneMolecularMononuclearParentsResearchResearch PersonnelResourcesSolutionsSourceSpectrum AnalysisUnited States National Institutes of Healthabsorptioncatalystdesigndimerelectron densityelectronic structureoxidationphenolate
项目摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
The aim of the current project is the synthesis and characterization of high-valent Fe-oxo complexes and their application as catalysts for selective C-H bond activation. Our strategy for stabilizing high-valent diiron units involves increasing the electron density at the iron ions by using strongly electron-donating ligands. For the ligands of the first generation, these involved strongly electron-donating s- and p-donors, namely phenolates. Detailed investigations of these complexes, particularly by -ray absorption spectroscopy (XAS), revealed that 1) the oxidation is ligand-centered and not metal-centered and 2) the oxidized species dissociate into mononuclear species. We used these results for the optimization of the ligand design. The new dinucleating ligands of the second generation have been synthesized and first investigations on their FeIIFeII, FeIIFeIII, and FeIIIFeIII complexes demonstrate the suitability of these complexes for generating high-valent dinuclear complexes, which should result in metal-centered oxidations and should possess higher stability as dinuclear entities. We propose the use of XAS to investigate the molecular and electronic structures of the parent complexes in solution as well as of the one- and two-electron oxidized species.
这个子项目是众多研究子项目之一
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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SERENA D DE BEER GEORGE其他文献
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{{ truncateString('SERENA D DE BEER GEORGE', 18)}}的其他基金
XES AND XAS STUDIES OF SOLUBLE METHANE MONOOXYGENASE
可溶性甲烷单加氧酶的 XES 和 XAS 研究
- 批准号:
8362359 - 财政年份:2011
- 资助金额:
$ 0.03万 - 项目类别:
XAS CHARACTERIZATION OF HIGH-VALENT IRON DIMERS RELEVANT TO METHANE MONOOXGENASE
与甲烷一氧化酶相关的高价铁二聚体的 XAS 表征
- 批准号:
8362238 - 财政年份:2011
- 资助金额:
$ 0.03万 - 项目类别:
IRON K-BETA XES STUDIES OF THE NITROGENASE ENZYME SYSTEM AND MODELS
固氮酶系统和模型的铁 K-β XES 研究
- 批准号:
8362061 - 财政年份:2011
- 资助金额:
$ 0.03万 - 项目类别:
COPPER BINDING TO ALPHA-SYNUCLEIN, THE PARKINSON'S PROTEIN
铜与帕金森病蛋白 α-突触核蛋白的结合
- 批准号:
8362168 - 财政年份:2011
- 资助金额:
$ 0.03万 - 项目类别:
COPPER BINDING TO ALPHA-SYNUCLEIN, THE PARKINSON'S PROTEIN
铜与帕金森病蛋白 α-突触核蛋白的结合
- 批准号:
8170119 - 财政年份:2010
- 资助金额:
$ 0.03万 - 项目类别:
XES AND XAS STUDIES OF SOLUBLE METHANE MONOOXYGENASE
可溶性甲烷单加氧酶的 XES 和 XAS 研究
- 批准号:
8170364 - 财政年份:2010
- 资助金额:
$ 0.03万 - 项目类别:
IRON K-BETA XES STUDIES OF THE NITROGENASE ENZYME SYSTEM AND MODELS
固氮酶系统和模型的铁 K-β XES 研究
- 批准号:
8169942 - 财政年份:2010
- 资助金额:
$ 0.03万 - 项目类别:
XAS STUDIES OF HIGH-VALENT FE MODEL COMPLEXES RELEVANT TO METHANE MONOOXYGENASE
甲烷单加氧酶相关高价FE模型复合物的XAS研究
- 批准号:
8170046 - 财政年份:2010
- 资助金额:
$ 0.03万 - 项目类别:
XAS STUDIES OF HIGH-VALENT FE MODEL COMPLEXES RELEVANT TO METHANE MONOOXYGENASE
甲烷单加氧酶相关高价FE模型复合物的XAS研究
- 批准号:
7954370 - 财政年份:2009
- 资助金额:
$ 0.03万 - 项目类别: