PROTEOMIC ANALYSIS OF THE HUMAN KINETOCHORE
人类动粒的蛋白质组学分析
基本信息
- 批准号:8171375
- 负责人:
- 金额:$ 0.08万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-09-01 至 2011-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
We are currently investigating human kinetochore composition and organization using an
affinity tagging strategy to isolate known and novel human kinetocore proteins and
kinetochore protein complexes. We have developed a combined approach to examine the
cellular localization of a protein and conduct a high affinity purification of that protein from
human tissue culture cells (Localization and Affinity Purification - LAP tag). Using this
approach, we have isolated more than 20 human kinetochore proteins, including at least 10
novel kinetochore proteins. This ongoing analysis will attempt to characterize the full range
of human kinetochore proteins and examine their interactions and organization.
这个子项目是众多研究子项目之一
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Iain McPherson Cheeseman其他文献
Iain McPherson Cheeseman的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Iain McPherson Cheeseman', 18)}}的其他基金
Zeiss LSM 980 with Airyscan 2 confocal microscope system
配备 Airyscan 2 共焦显微镜系统的 Zeiss LSM 980
- 批准号:
10177119 - 财政年份:2021
- 资助金额:
$ 0.08万 - 项目类别:
Molecular control of centromere specification and kinetochore assembly
着丝粒规格和着丝粒组装的分子控制
- 批准号:
9107890 - 财政年份:2015
- 资助金额:
$ 0.08万 - 项目类别:
Molecular control of centromere specification and kinetochore assembly
着丝粒规格和着丝粒组装的分子控制
- 批准号:
8964182 - 财政年份:2015
- 资助金额:
$ 0.08万 - 项目类别:
Molecular Analysis of the Kinetochore-Microtubule Interface
着丝粒-微管界面的分子分析
- 批准号:
8299046 - 财政年份:2009
- 资助金额:
$ 0.08万 - 项目类别:
Molecular Analysis of the Kinetochore-Microtubule Interface
着丝粒-微管界面的分子分析
- 批准号:
8755297 - 财政年份:2009
- 资助金额:
$ 0.08万 - 项目类别:
Molecular Analysis of the Kinetochore-Microtubule Interface
着丝粒-微管界面的分子分析
- 批准号:
7903228 - 财政年份:2009
- 资助金额:
$ 0.08万 - 项目类别:
相似海外基金
Cellular membrane affinity chromatography kit for drug discovery
用于药物发现的细胞膜亲和层析试剂盒
- 批准号:
10506915 - 财政年份:2021
- 资助金额:
$ 0.08万 - 项目类别:
Cellular membrane affinity chromatography kit for drug discovery
用于药物发现的细胞膜亲和层析试剂盒
- 批准号:
10325006 - 财政年份:2021
- 资助金额:
$ 0.08万 - 项目类别:
SBIR Phase I: A New Class of Immobilized Metal Affinity Chromatography Resins
SBIR 第一阶段:一类新型固定金属亲和色谱树脂
- 批准号:
1746198 - 财政年份:2018
- 资助金额:
$ 0.08万 - 项目类别:
Standard Grant
Marine speciation of nickel using immobilized nickel affinity chromatography
使用固定镍亲和色谱法测定镍的海洋形态
- 批准号:
512537-2017 - 财政年份:2017
- 资助金额:
$ 0.08万 - 项目类别:
University Undergraduate Student Research Awards
I-Corps: Commercialization of Immobilized Metal Affinity Chromatography Resins Based on Nanomaterials
I-Corps:基于纳米材料的固定化金属亲和层析树脂的商业化
- 批准号:
1404605 - 财政年份:2014
- 资助金额:
$ 0.08万 - 项目类别:
Standard Grant
Antibody Purification via Affinity Chromatography that Utilizes the Unconventional Nucleotide Binding Site
利用非常规核苷酸结合位点通过亲和色谱法纯化抗体
- 批准号:
1263713 - 财政年份:2013
- 资助金额:
$ 0.08万 - 项目类别:
Continuing Grant
Development of multivalent DNA network based affinity chromatography diagnostics for isolating circulating tumour cells
开发基于多价 DNA 网络的亲和色谱诊断法,用于分离循环肿瘤细胞
- 批准号:
425749-2012 - 财政年份:2012
- 资助金额:
$ 0.08万 - 项目类别:
Postgraduate Scholarships - Master's
Next-Generation Affinity Chromatography with PEGylated Ligands
使用聚乙二醇化配体的新一代亲和色谱法
- 批准号:
1159886 - 财政年份:2012
- 资助金额:
$ 0.08万 - 项目类别:
Standard Grant
Immobilized zirconium ion affinity chromatography for specific enrichment of phosphoproteins
用于磷蛋白特异性富集的固定化锆离子亲和层析
- 批准号:
19560760 - 财政年份:2007
- 资助金额:
$ 0.08万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Accelerating drug discovery using frontal affinity chromatography/mass spectrometry
使用正面亲和色谱/质谱加速药物发现
- 批准号:
234753-2000 - 财政年份:2003
- 资助金额:
$ 0.08万 - 项目类别:
Collaborative Research and Development Grants