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ACTIN-MEDIATED CONTRACTILITY EFFECTS ON CAPILLARY MORPHOGENESIS IN TISSUES

ACTIN-MEDIATED CONTRACTILITY EFFECTS ON CAPILLARY MORPHOGENESIS IN TISSUES
肌动蛋白介导的组织毛细血管形态发生的收缩效应
批准号：
8170960
负责人：
Andrew J Putnam
金额：
$4.15万
依托单位：
UNIVERSITY OF CALIFORNIA-IRVINE
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-08-01 至 2011-07-31
来源：
https://reporter.nih.gov/project-details/8170960
关键词：
ActinsBlood capillariesComputer Retrieval of Information on Scientific Projects DatabaseFibrinFundingGrantHydrogelsImplantInstitutionMediatingModelingMorphogenesisPECAM1 geneResearchResearch PersonnelResourcesSourceTissue StainsTissuesUnited States National Institutes of Healthangiogenesiscapillaryinhibitor/antagonist

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A bead-angiogenesis model is implanted in fibrin hydrogels of varied stiffness in this study. They are furthermore treated with actin contractility inhibitors. Angiogenic vessel sprouts that develop on the beads are then analyzed in terms of actin contractility presence as well as morphological differences. The tissues are stained for actin as well as CD31 to determine the effects of contractility inhibition on capillary morphogenesis.
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2023 Biomaterials and Tissue Engineering
  • 批准号：
    10675948
  • 项目类别：
  • 资助金额：
    $1.3万
  • 财政年份：
    2023
  • 负责人：
    Andrew J Putnam
  • 依托单位：
    GORDON RESEARCH CONFERENCES
Preformed vascular modules designed for inosculation with host tissue
Preformed vascular modules designed for inosculation with host tissue
Preformed vascular modules designed for inosculation with host tissue
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