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MECH OF CONDUCTION SLOWING DURING MYOCARDIAL STRETCH BY VENT VOL LOADING

MECH OF CONDUCTION SLOWING DURING MYOCARDIAL STRETCH BY VENT VOL LOADING
通气量负荷导致心肌舒张时传导减慢的机制
批准号：
8169348
负责人：
Sanjiv M Narayan
金额：
$2.23万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-05-01 至 2011-04-30
来源：
https://reporter.nih.gov/project-details/8169348
关键词：
Computer Retrieval of Information on Scientific Projects DatabaseEconomic InflationElectric CapacitanceFundingGrantInstitutionMembraneMyocardialResearchResearch PersonnelResistanceResourcesSourceStretchingUnited States National Institutes of HealthVentVentricular

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Passive ventricular loading by volume inflation reversibly slows electrical conduction, but the mechanism behind this slowing remains unclear. We investigates the contributions of stretch-activated channels, altered membrane excitability, and changes in intercellular resistance or effective membrane capacitance during volume loading as the mechanism behind conduction slowing.
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