POLYMORPHISM IN MACAQUE ANTI-RETROVIRAL FACTOR TRIM5ALPHA
猕猴抗逆转录病毒因子 TRIM5ALPHA 的多态性
基本信息
- 批准号:8172849
- 负责人:
- 金额:$ 20.24万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-05-01 至 2011-04-30
- 项目状态:已结题
- 来源:
- 关键词:Anti-Retroviral AgentsComputer Retrieval of Information on Scientific Projects DatabaseFundingGenetic PolymorphismGenetic Population StudyGrantHIV-1InfectionInstitutionKnowledgeMacacaMediatingModelingOutcomePathogenesisPrimatesProteinsResearchResearch PersonnelResourcesSIVSourceUnited States National Institutes of Health
项目摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
The primate TRIM5alpha protein mediates a potent, post-entry block to retroviral infection. We are studying the population-genetics of primate TRIM5alpha and using this knowledge to develop better models for HIV-1 replication and pathogenesis, and in ascertaining the effects of TRIM5alpha polymorphism on differential outcome during SIV infection.
这个子项目是众多研究子项目之一
项目成果
期刊论文数量(0)
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科研奖励数量(0)
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Welkin E Johnson其他文献
Assisted suicide for retroviruses
因逆转录病毒导致的协助自杀
- DOI:
10.1038/nbt0607-643 - 发表时间:
2007-06-01 - 期刊:
- 影响因子:41.700
- 作者:
Welkin E Johnson - 通讯作者:
Welkin E Johnson
Welkin E Johnson的其他文献
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{{ truncateString('Welkin E Johnson', 18)}}的其他基金
POLYMORPHISM IN MACAQUE ANTI-RETROVIRAL FACTOR TRIM5ALPHA
猕猴抗逆转录病毒因子 TRIM5ALPHA 的多态性
- 批准号:
8357939 - 财政年份:2011
- 资助金额:
$ 20.24万 - 项目类别: