课题基金 / 基金详情

POLYMORPHISM IN RHESUS MACAQUE ANTI-RETROVIRAL FACTOR TRIM5ALPHA

POLYMORPHISM IN RHESUS MACAQUE ANTI-RETROVIRAL FACTOR TRIM5ALPHA
恒河猴抗逆转录病毒因子 TRIM5ALPHA 的多态性
批准号：
7958356
负责人：
Welkin E Johnson
金额：
$20.61万
依托单位：
HARVARD MEDICAL SCHOOL
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-05-01 至 2010-04-30
来源：
https://reporter.nih.gov/project-details/7958356
关键词：
Anti-Retroviral AgentsComputer Retrieval of Information on Scientific Projects DatabaseFundingGenetic PolymorphismGenetic Population StudyGrantHIV-1InfectionInstitutionKnowledgeMacaca mulattaMediatingModelingNew EnglandOutcomePathogenesisPrimatesProteinsResearchResearch PersonnelResourcesSIVSourceUnited States National Institutes of Healthbase

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primate TRIM5alpha protein mediates a potent, post-entry block to retroviral infection. We are studying the population-genetics of primate TRIM5alpha and using this knowledge to develop better models for HIV-1 replication and pathogenesis, and in ascertaining the effects of TRIM5alpha polymorphism on differential outcome during SIV infection.
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POLYMORPHISM IN MACAQUE ANTI-RETROVIRAL FACTOR TRIM5ALPHA
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  • 项目类别：
  • 资助金额：
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  • 财政年份：
    2011
  • 负责人：
    Welkin E Johnson
  • 依托单位：
    HARVARD MEDICAL SCHOOL
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  • 财政年份：
    2011
  • 负责人：
    Welkin E Johnson
  • 依托单位：
    BOSTON COLLEGE
Intrinsic Immunity and AIDS
  • 批准号：
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  • 项目类别：
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  • 财政年份：
    2011
  • 负责人：
    Welkin E Johnson
  • 依托单位：
    BOSTON COLLEGE
Intrinsic Immunity and AIDS
  • 批准号：
    8472603
  • 项目类别：
  • 资助金额：
    $58.0万
  • 财政年份：
    2011
  • 负责人：
    Welkin E Johnson
  • 依托单位：
    BOSTON COLLEGE