A NOVEL ASSAY FOR ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY

抗体依赖性细胞介导的细胞毒性的新型检测方法

• 批准号: 8172893
• 负责人: David T Evans
• 金额: $ 20.24万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172893
• 关键词: Antibodies; Biological Assay; Cells; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Measures; Mediating; Plasma; Research; Research Personnel; Resources; SIV; Source; United States National Institutes of Health; antibody-dependent cell cytotoxicity; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We developed a novel assay for measuring antibody titers in plasma capable of mediating antibody-dependent cell-mediated cytotoxicity against simian immunodeficiency virus infected cells.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们开发了一种新的测定血浆中抗体滴度的方法，该方法能够介导抗体依赖性细胞介导的细胞毒性，对抗猴免疫缺陷病毒感染的细胞。