Hearing Loss and Aging

听力损失和衰老

• 批准号: 8025277
• 负责人: FRANK R LIN
• 金额: $ 23.67万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-12-01 至 2015-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8025277
• 关键词: Accounting; Address; Adult; Aging; Attitude; Auditory; Baltimore; Biometry; Caring; Characteristics; Childhood; Clinical; Clinical Research; Clinical Trials; Cochlear Implants; Cochlear implant procedure; Cognition; Cognitive Science; Communication; Communication impairment; Data; Data Set; Dementia; Doctor of Philosophy; Education; Elderly; Enrollment; Environment; Environmental Risk Factor; Epidemiology; Evaluation Studies; Expenditure; Eye; Faculty; Family; Family member; Foundations; Future; Geriatrics; Gerontology; Head and Neck Surgery; Health; Health Expenditures; Hearing; Hearing Aids; High Prevalence; Impaired cognition; Individual; Interdisciplinary Study; Intervention; K-Series Research Career Programs; Knowledge; Longitudinal Studies; Manuals; Measures; Mediating; Medical; Mental Depression; Mentors; Mentorship; Methodology; Metric; Modality; Modeling; Morbidity - disease rate; National Institute on Aging; Ophthalmology; Otolaryngology; Otology; Outcome; Outcomes Research; Patients; Perception; Physical Function; Prevalence; Preventive; Prospective Studies; Public Health; Public Health Schools; Recruitment Activity; Rehabilitation therapy; Reporting; Research; Research Personnel; Resources; Risk; Role; Science; Social Network; Social isolation; Spouses; Structure; Study Section; Surveys; Testing; Therapeutic; Women' s Health; Work; World Health Organization; adverse outcome; aging population; base; career; clinical practice; cognitive reserve; cost; economic implication; economic outcome; evidence base; experience; frailty; functional decline; functional outcomes; health economics; health related quality of life; hearing impairment; improved; interdisciplinary approach; interdisciplinary collaboration; medical schools; member; mortality; novel; post intervention; prospective; skills; social; social cognition

DESCRIPTION (provided by applicant): Dr. Frank Lin is a junior faculty member in the Department of Otolaryngology-Head & Neck Surgery at the Johns Hopkins School of Medicine where his clinical practice is dedicated to hearing loss and otology. He previously completed a Ph.D in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health where he applied conceptual models of functioning developed by the World Health Organization to the assessment of pediatric cochlear implantation (CI). With the support of this Mentored Career Development Award, Dr. Lin seeks to better understand the impact of hearing loss on the health and functioning of older adults and the role of therapeutic modalities such as CI in mitigating these effects. Dr. Lin will enhance his research knowledge and skills with coursework in geriatrics and biostatistics, receive directed mentorship by an interdisciplinary team of experienced clinical researchers, and be immersed in the interdisciplinary research and clinical environments of the Longitudinal Studies Section of the National Institute on Aging, the Johns Hopkins Center on Aging and Health, the Johns Hopkins Dana Center for Preventive Ophthalmology, and the Johns Hopkins Listening Center. This CDA will provide Dr. Lin with the resources that he needs to become an independent investigator and future leader in hearing loss and clinical research. Building on his prior research experience in utilizing conceptual models of health outcomes, Dr. Lin has developed a novel framework to understand and study the impact of hearing loss on older adults that draws on the fields of cognitive psychology, social epidemiology, gerontology, and the hearing sciences. In Aim 1, he will use four established prospective datasets to study the effects of hearing loss on domains of cognition, social isolation, dementia, functional decline, health care expenditures, and mortality. This work will establish the basis for the impact of hearing loss in aging. In Aim 2, he will prospectively recruit adult patients undergoing CI at the Listening Center into a study examining the effects of CI on domains of health and functioning. This work will inform strategies for hearing aid and cochlear implant delivery and future clinical trials of hearing loss interventions. PUBLIC HEALTH RELEVANCE: The impact of hearing loss on older adults is poorly understood despite the growing prevalence of hearing loss and the rapidly aging population. Studying the effects of hearing loss on critical domains of aging such as cognition, dementia, and functioning will allow us to understand how aural rehabilitative modalities and preventative interventions could be utilized to improve the health and functioning of older adults.

描述（由申请人提供）：Frank Lin博士是约翰霍普金斯医学院耳鼻咽喉头颈外科系的初级教员，他的临床实践致力于听力损失和耳科。他之前在约翰霍普金斯彭博公共卫生学院完成了临床研究博士学位，在那里他将世界卫生组织开发的功能概念模型应用于儿童人工耳蜗植入（CI）的评估。在这个指导职业发展奖的支持下，林博士寻求更好地了解听力损失对老年人健康和功能的影响，以及CI等治疗方式在减轻这些影响方面的作用。林博士将通过老年医学和生物统计学课程提高他的研究知识和技能，接受经验丰富的临床研究人员组成的跨学科团队的指导，并沉浸在国家老龄化研究所纵向研究部分，约翰霍普金斯老龄与健康中心，约翰霍普金斯达纳预防眼科中心，和约翰霍普金斯听力中心。该CDA将为林博士提供他成为听力损失和临床研究的独立研究者和未来领导者所需的资源。基于他之前在利用健康结果概念模型方面的研究经验，林博士开发了一个新的框架来理解和研究听力损失对老年人的影响，该框架借鉴了认知心理学，社会流行病学，老年学和听力科学领域。在目标1中，他将使用四个已建立的前瞻性数据集来研究听力损失对认知、社会隔离、痴呆、功能衰退、医疗保健支出和死亡率等领域的影响。这项工作将为老龄化对听力损失的影响奠定基础。在目标2中，他将前瞻性地招募在听力中心接受CI治疗的成年患者，研究CI对健康和功能领域的影响。这项工作将为助听器和人工耳蜗植入物的交付以及未来听力损失干预的临床试验提供信息。 公共卫生关系：听力损失对老年人的影响知之甚少，尽管听力损失的患病率越来越高，人口迅速老龄化。研究听力损失对认知、痴呆和功能等衰老关键领域的影响将使我们了解如何利用听觉康复方式和预防性干预措施来改善老年人的健康和功能。