Developing an integrated systems and synthetic biology platform to expand the product spectrum of acetogens

开发集成系统和合成生物学平台以扩大产乙酸剂的产品范围

• 批准号: LP140100213
• 负责人: Prof Lars Nielsen
• 金额: $ 42.3万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-03-06 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP140100213
• 关键词: Developing; integrated; systems; synthetic; biology

This project aims to advance a waste gas fermentation process to enable the production of sustainable aviation fuel molecules for the first time. LanzaTech are world leaders in microbial gas fermentation and have produced ethanol at large scale in China. This project aims to combine the LanzaTech process with systems biology expertise at The University of Queensland to go beyond ethanol to deliver new value-added products such as butanediol and farnesene. To achieve this aim the project will explore, understand and overcome fundamental energy and metabolic limitations in the production microorganism. Achieving the aims will be of direct relevance to SkyNRG and the new Brisbane Bioport on their path to deliver sustainable fuel to Brisbane Airport.

该项目旨在推进废气发酵工艺，首次实现可持续航空燃料分子的生产。LanzaTech在微生物气体发酵领域处于世界领先地位，并已在中国大规模生产乙醇。该项目旨在将LanzaTech工艺与昆士兰大学的系统生物学专业知识结合起来，超越乙醇，提供新的增值产品，如丁二醇和法尼烯。为了实现这一目标，该项目将探索、理解和克服生产微生物的基本能量和代谢限制。实现这些目标将直接关系到SkyNRG和新的布里斯班生物港向布里斯班机场提供可持续燃料的道路。