Translational Research Training in Sleep Medicine

描述(由申请人提供)：这是T32 HL082610-04“睡眠医学中的转化性研究培训”的第一个竞争性续展申请。该培训计划的目的是培训未来一代临床和基础睡眠研究人员，使他们掌握睡眠医学的翻译方法。我们的理念是，当睡眠医学的研究培训内容是翻译性的、其教员是多学科的、其结果是可衡量的和基于能力的时，它是最有效的。在我们最初的31年半时间里，我们在运营这个项目方面吸取了宝贵的经验教训，并取得了初步成功，这得到了我们的外部咨询委员会(EAB)的赞扬。在我们最初的8名博士后研究员中，1人获得了K奖，另外4人已经或将在未来6个月内提交。他们总共出版、出版或提交了39份同行评议的手稿，并在培训期间/之后提交了36份摘要。我们的10名医学生已经提交了6篇摘要，并发表了一篇第一次发表的同行评议论文。我们根据学员、大学顾问委员会(UAB)和EAB的评估，系统地检查了我们的计划。根据这些评估，我们建议对培训方案和我们的招聘战略进行具体修改。培训计划包括两个部分：1)为从肺部医学、精神病学、神经学和内科专业招聘的MD科学家和通过跨学科生物医学研究生计划、临床心理学实习和流行病学研究生计划在全国和当地招聘的博士毕业生提供2-3年的博士后培训奖学金。2)医科学生的研究经历，包括两条途径：a)暑期研究计划；b)贯穿4年医学院的纵向“学术项目”。我们建议每年招收4名医学生参加暑期项目，4名学生参加纵向学术项目。博士后和医学生实习生受益于多样化的多学科培训学院，受益于匹兹堡大学开展睡眠研究的出色资源，以及强大的机构支持，包括临床和翻译科学研究所以及学术职业发展办公室内的项目。我们使用多种策略来招募不同的、多学科的实习生。博士后培训计划采用了具体的、可量化的培训里程碑，强调有指导的研究；出版物；职业发展奖励的制定；以及必修和选修的教学课程，包括负责任的研究行为。医科学生的培训同样强调科学推理和有指导的重点研究。正在进行的评估是该计划的一个组成部分，包括UAB和EAB投入。具体方案和机构努力的目标是招募人数不足的少数族裔受训人员和残疾人。

DESCRIPTION (provided by applicant): This is the first competing renewal application of T32 HL082610-04, "Translational Research Training in Sleep Medicine." The aim of this training program is to train the future generation of clinical and basic sleep researchers in a translational approach to sleep medicine. Our philosophy is that research training in sleep medicine is most effective when its content is translational, its faculty multidisciplinary, and its outcomes measurable and competency-based. During our initial 31/2 years, we have learned valuable lessons on running this program and have enjoyed early success, which was commended by our External Advisory Board (EAB). Of our initial 8 postdoctoral fellows, one has received a K award, and four others have or will submit within the next 6 months. In aggregate, they have 39 peer-reviewed manuscripts published, in press, or submitted, and 36 abstracts during/after their training. Our 10 medical students have submitted 6 abstracts and published one first-authored peer-reviewed paper. We have systematically examined our program with evaluations from the trainees, a University Advisory Board (UAB), and EAB. Based on these evaluations, we propose specific modifications in the training program and in our recruitment strategies. The training program includes two components: 1) A 2-3 year postdoctoral training fellowship for MD scientists recruited from pulmonary medicine, psychiatry, neurology, and internal medicine programs and PhD graduates recruited nationally and locally through the Interdisciplinary Biomedical Graduate Program, clinical psychology internships, and the epidemiology graduate program. We propose to maintain the current program size of four fellows for Years 06- 10. 2) Research experiences for medical students, which comprise two pathways: a) a summer research program; b) a longitudinal "scholarly project" running through 4 years of medical school. We propose to enroll 4 medical students each year in the summer program, and 4 students in the longitudinal scholarly project. Postdoctoral and medical student trainees benefit from a diverse, multidisciplinary Training Faculty; from outstanding resources for conducting sleep research at the University of Pittsburgh; and from strong institutional support, including programs within the Clinical and Translational Science Institute and the Office of Academic Career Development. We use multiple strategies to recruit diverse, multidisciplinary trainees. The postdoctoral training program employs specific, quantifiable training milestones emphasizing mentored research; publications; the development of career development awards; and required and elective didactic coursework including responsible conduct of research. Medical student training likewise emphasizes scientific reasoning and focused, mentored research. Ongoing evaluation is an integral component of the program, and includes UAB and EAB input. Program-specific and institutional efforts are aimed at the recruitment of underrepresented minority trainees and individuals with disabilities.