MSU Clinical Center Animal Facility HVAC Upgrade

描述(由申请者提供)：项目摘要：密歇根州立大学(MSU)目前正在进行总体规划工作，以确保最先进的设施继续用于实验动物的研究和教学。一些实验动物设施即将达到需要升级的年龄，该机构将根据设施的使用、状况和长期生存能力进行选择性投资，因此并不是所有的设施都将继续投资，从而导致停止使用动物收容所。这项研究的初步结论是，我们主要的动物护理设施-临床中心动物设施(CCAF)-将需要更新工程系统。CCAF是密歇根州立大学用于支持生物医学和行为研究的主要实验动物设施。在这些升级之后，该设施将支持超过46名教职员工的研究。密歇根州立大学将与NIH的资金比例超过3：1。拟议项目的重点是升级CCAF的供暖、通风和空调(HVAC)系统。虽然CCAF已有近35年的历史，但它是一个设计非常好的设施。该设施的布局灵活，可以容纳各种各样的研究，并可以水平或垂直扩展，以满足未来的增长。每个楼层上方都有一个全高的空隙空间，使这一暖通空调升级项目能够经济高效地进行。CCAF暖通空调系统是独创的，其可靠寿命即将结束。该改造项目将替换现有老化部件，并增加系统冗余和集中报警。拟议的翻修将通过更换老化的暖通空调设备并确保在新设备发生故障或计划维护期间提供冗余，确保保持严格的环境控制，以实现最佳动物健康和福利以及可靠的研究数据。一旦升级，这个设施将在一些较小的校园动物设施的翻新和维护期间提供空间，在被认为不是最佳翻新的设施中为动物提供住所，并容纳新教员在再生医学、神经科学和传染病、疾病分子机制、生物医学工程和胃肠病/微生物生态学领域的研究。密歇根州立大学是被卡内基基金会指定为研究型大学的一所公立土地赠与机构。密歇根州立大学是美国第一所教授科学农业的高等学府，它提供了由17所授予学位的学院提供的200多个学习项目，吸引了世界各地的学者。作为一所综合性研究型大学，密歇根州立大学拥有5000名教职员工、6300名后勤人员、3.64万多名本科生和近10800名研究生和专业学生。密歇根州立大学2009-2010学年的总招生人数超过47,200人，使密歇根州立大学成为美国十大最大的大学之一。

DESCRIPTION (provided by applicant): Project Summary: Michigan State University (MSU) is currently undertaking a master planning exercise to ensure that state-of- the-art facilities continue to be used to house laboratory animals for research and teaching. Several of the laboratory animal facilities are reaching the age where they will require upgrades and the institution will make selective investments based on the use, condition and long-term viability of the facility, thus not all facilities will continue to be invested in resulting in discontinued use for animal housing. An initial conclusion from this study is that our premier animal care facility, the Clinical Center Animal Facility (CCAF), will require renovation of the engineering systems. The CCAF is the major laboratory animal facility at MSU used to support the conduct of biomedical and behavioral research. Following these upgrades the facility will support the research of over 46 faculty members. MSU will match the NIH funding in excess of a 3:1 ratio. The proposed project focuses on upgrading the heating, ventilation and air-conditioning (HVAC) system of the CCAF. Although almost 35 years old, the CCAF is an extremely well-designed facility. The layout of the facility is flexible to accommodate a wide variety of research and can be expanded horizontally or vertically for future growth. There is a full height interstitial space above each of the floors allowing this HVAC upgrade project to be carried out cost effectively. The CCAF HVAC system is original and nearing the end of its reliable lifespan. This renovation project will replace the current aged components, and add redundancy and central alarming of the system. The proposed renovation will ensure that tight environmental controls are maintained for optimal animal health and welfare and reliable research data, by replacing the aging HVAC equipment and ensuring redundancy should the new equipment malfunction or during times of planned maintenance. Once upgraded, this facility will provide space during renovation and maintenance of some of the smaller campus animal facilities, housing for animals in facilities deemed not optimal to renovate, and to accommodate the research of new faculty in the areas of regenerative medicine, neuroscience, and infectious disease, molecular mechanisms of disease, biomedical engineering and gastroenterology /microbial ecology. MSU is a public, land-grant institution designated as a Research-Extensive university by the Carnegie Foundation. The first institution of higher learning in the United States to teach scientific agriculture, MSU offers more than 200 programs of study offered by 17 degree-granting colleges that attract scholars worldwide. As a comprehensive research university, MSU has 5,000 faculty and academic staff, 6,300 support staff, more than 36,400 undergraduate and nearly 10,800 graduate and professional students. Total enrollment for 2009- 2010 exceeded 47,200, making MSU one of the ten largest universities in the United States.