9 Intl Symposium - Functional Neuroreceptor Mapping of the Living Brain NRM 2012

第 9 届国际研讨会 - 活体大脑功能神经感受器图谱 NRM 2012

• 批准号: 8203850
• 负责人: Gwenn S Smith
• 金额: $ 4.3万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-15 至 2012-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8203850
• 关键词: Academia; Aging; Air; Alzheimer' s Disease; Amyloid; Amyloid beta-Protein; Amyloid deposition; Animals; Area; Award; Baltimore; Basic Science; Biological Markers; Biomedical Engineering; Books; Brain; Brain Diseases; Brain imaging; Central Nervous System Agents; Chemistry; Clinical; Clinical Research; Cognition; Collaborations; Communication; Corticotropin-Releasing Hormone; Data; Development; Diagnostic; Disease; Dopamine; Drug Industry; Educational workshop; Electronics; Europe; Event; Faculty; Fellowship; Fostering; Functional Magnetic Resonance Imaging; Functional disorder; Goals; Grant; Human; Image; Imaging Techniques; Inflammation; Institution; International; Intramural Research Program; Life; Ligands; Location; Maps; Maryland; Measures; Mental Depression; Mental disorders; Mentors; Mentorship; Methodology; Methods; Modality; Molecular Target; Movement Disorders; National Institute of Biomedical Imaging and Bioengineering; National Institute of Drug Abuse; National Institute of Mental Health; National Institute of Neurological Disorders and Stroke; National Institute on Alcohol Abuse and Alcoholism; Nerve Degeneration; Neurobiology; Neurodegenerative Disorders; Neuropharmacology; Neurosciences; Neurotransmitters; North America; Opiates; Outcome; Parkinson' s Dementia; Peer Review; Pharmaceutical Preparations; Photons; Physicians; Positron-Emission Tomography; Process; Psychopharmacology; Publications; Publishing; Radiochemistry; Radiopharmaceuticals; Research; Research Personnel; Resolution; Resources; Schizophrenia; Scientist; Sensory Receptors; Serotonin; Signal Transduction; Societies; Stress; System; Technology; Testing; Time; Tomography, Computed, Scanners; Training; Translational Research; United States National Institutes of Health; Universities; Work; abstracting; addiction; amyloid imaging; base; clinical application; cognitive neuroscience; drug development; drug discovery; experience; follow-up; imaging modality; improved; in vivo; instrument; instrumentation; interest; lectures; medical schools; meetings; molecular imaging; monoamine; multidisciplinary; multimodality; neurochemistry; neurogenesis; neuroimaging; neuroinflammation; neuropathology; neuropsychiatry; neurotransmission; neurotransmitter metabolism; nonhuman primate; noradrenaline transporter; posters; pre-clinical; programs; psychologic; radiotracer; receptor; receptor binding; research and development; single photon emission computed tomography; symposium; web site

DESCRIPTION (provided by applicant): We seek $50,000 in support from NIMH, and NIDA, NIAAA, NINDS, NIA, and NIBIB to host the 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM12) from August 9 - 11, 2012 in Baltimore, MD. This symposium is a biennial meeting of researchers and physicians in academia and the pharmaceutical industry whose research focuses on the development of non-invasive imaging techniques, such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT), and other molecular imaging methods to functionally characterize and quantify neurotransmitters (e.g., serotonin-2A, dopamine-D2) and other neurobiological processes (e.g., amyloid, neuroinflammation) in the living brain. The overarching goals of scientific sessions of the meeting are to apply noninvasive neuroimaging methods to: 1) improve the understanding of the pathophysiology of neurodegenerative diseases and psychiatric disorders, addictive disorders, and aging and psychological processes; 2) to develop improved methods of quantifying neuroreceptor function in vivo; 3) to effectively use molecular imaging techniques to accelerate the process of central nervous system (CNS) drug development; 4) to expand molecular imaging measures to new areas such as imaging psychological processes (e.g., cognition, stress); and 5) to develop methods and applications of multimodality imaging (e.g., PET/fMRI). The scientific program for the meeting will focus on basic and clinical research that is of direct relevance to NIH Neuroscience sponsored research. The main component of the symposium program will include approximately 50 platform presentations and 150 poster abstract presentations. The program will also include three plenary lectures, three panel thematic discussions of key issues led by 4-5 experts each, and training and networking events. This symposium will leverage the breadth of expertise of a truly international and multidisciplinary group of researchers and physicians, who work in the area of functional neuroimaging and related fields, to identify and explore translational research opportunities that may advance clinical diagnostics and drug development and to establish and foster communication, collaboration, and fellowship among the group. A junior investigator award program will enable trainees to attend the meeting and to present their work to senior colleagues. A key outcome of the symposium will be the program and abstract publication book, which will be made available to meeting delegates and NIH program officials and is planned as an electronic .pdf file to post on the symposium website for a minimum of 1 year after the conference for global dissemination. PUBLIC HEALTH RELEVANCE: This is a conference grant to support the 9th International Neuroreceptor Mapping Meeting that is held alternately in North America and Europe bi-annually. There is no official society, but this has been an extremely well attended meeting by a loyal group of about 250-300 basic and translational scientists who are dedicated to all aspects of neuroreceptor mapping (i.e., PET and SPECT imaging of radiopharmaceuticals that image brain neuroreceptor and neurotransmitter systems). This meeting will continue to promote the state of the art of this field from radiochemistry to clinical applications, and will feature focus areas including advances in integrating cognitive neuroscience (which is traditionally a part of fMRI) with neuroreceptor mapping (traditionally imaging of drugs and ligands and a part of drug development), as well as advances in neuroreceptor and amyloid imaging in neurodegeneration.

描述（由申请人提供）：我们寻求NIMH和NIDA，NIAAA，NINDS，NIA和NIBIB的50，000美元的支持，以举办2012年8月9日至11日在马里兰州巴尔的摩举行的第9届活脑功能神经受体映射国际研讨会（NRM 12）。该研讨会是学术界和制药行业研究人员和医生的两年一度的会议，其研究重点是非侵入性成像技术的发展，如正电子发射断层扫描（PET）和单光子发射计算机断层扫描（SPECT），以及其他分子成像方法，以功能表征和量化神经递质（例如，5-羟色胺-2A，多巴胺-D2）和其它神经生物学过程（例如，淀粉样蛋白，神经炎症）。会议科学会议的总体目标是应用非侵入性神经成像方法：1）提高对神经退行性疾病和精神疾病，成瘾性疾病，衰老和心理过程的病理生理学的理解; 2）开发量化体内神经受体功能的改进方法; 3）有效地利用分子成像技术来加速中枢神经系统（CNS）药物开发的过程; 4）将分子成像措施扩展到新的领域，例如成像心理过程（例如，认知，压力）;以及5）开发多模态成像的方法和应用（例如，PET/fMRI）。会议的科学计划将侧重于与NIH神经科学赞助的研究直接相关的基础和临床研究。研讨会计划的主要组成部分将包括大约50个平台演示和150个海报摘要演示。该计划还将包括三个全体讲座，三个小组专题讨论的关键问题，由4-5名专家领导，以及培训和网络活动。本次研讨会将利用一个真正的国际和多学科的研究人员和医生，谁在功能性神经影像学和相关领域的工作领域的专业知识的广度，以确定和探索转化研究的机会，可能会推进临床诊断和药物开发，并建立和促进沟通，合作，和团体之间的奖学金。初级调查员奖励方案将使受训人员能够参加会议，并向高级同事介绍他们的工作。研讨会的一个关键成果将是计划和摘要出版物，将提供给会议代表和NIH计划官员，并计划以电子.pdf文件的形式在研讨会网站上发布，至少在会议结束后1年内进行全球传播。 公共卫生相关性：这是一个会议补助金，以支持第九届国际神经感受器映射会议，该会议每两年在北美和欧洲交替举行。没有官方的协会，但这是一个非常好的会议，由大约250-300名基础和翻译科学家组成的忠诚小组参加，他们致力于神经受体绘图的各个方面（即，对脑神经受体和神经递质系统成像的放射性药物的PET和SPECT成像）。本次会议将继续促进该领域从放射化学到临床应用的最新技术水平，并将重点关注包括认知神经科学（传统上是功能磁共振成像的一部分）与神经受体映射（传统上是药物和配体的成像以及药物开发的一部分）相结合的进展，以及神经退行性疾病中神经受体和淀粉样蛋白成像的进展。