2011 Biological Molecules in the Gas Phase and in Solution GRC

2011 气相和溶液中的生物分子 GRC

• 批准号: 8193187
• 负责人: DAVID E. CLEMMER
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-15 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8193187
• 关键词: Academy; Address; Area; Bioinformatics; Biological; Biology; Blood Circulation; Carbohydrates; Chemicals; Chemistry; Collaborations; Communities; Development; Dissociation; Environment; Funding; Future; Gases; Goals; Individual; International; Label; Life; Mass Spectrum Analysis; Medicine; Methods; Modeling; Molecular; New Hampshire; Optics; Oral; Participant; Peptide Nucleic Acids; Pharmacy facility; Phase; Physics; Play; Postdoctoral Fellow; Protein Dynamics; Proteomics; Public Health; Research; Research Personnel; Role; Scientist; Series; Solutions; Solvents; Spectrum Analysis; Structure; Students; Supplementation; System; Talents; Travel; United States National Institutes of Health; Water; Work; aqueous; biological systems; computational chemistry; frontier; improved; interest; ion mobility; meetings; novel strategies; posters; programs; stem; success; symposium; tool

DESCRIPTION (provided by applicant): Support is requested for the Gordon Research Conference on "Biological Molecules in the Gas Phase and in Solution", which will take place during the week of July 31 to August 5, 2011 at Proctor Academy, Andover, New Hampshire. This Gordon Research Conference (GRC) will provide an international forum for discussing fundamental questions related to the structure and dynamics of proteins, peptides, nucleic acids, carbohydrates, and other molecular building blocks of life. One focus of this meeting is the characterization of biological molecules by mass spectrometry and related approaches (including chemical labeling, ion mobility and various dissociation methods). Another emphasis is on the interrogation of biomolecular systems by spectroscopic tools. In addition, the conference will highlight key computational and theoretical contributions. Some of the issues that will be addressed include the following: How do biological molecules behave once they have been deprived of their aqueous environment? How can gas phase methods be employed for obtaining structural information on biological molecules in solution? How do biological molecules interact with water? How do biological molecules behave in solvents other than water? The uniqueness of this meeting stems from its strongly interdisciplinary character, as it brings together experimentalists and theorists working at the interface of chemistry, biology, physics, and medicine. This GRC also provides a perfect opportunity for young scientists to interact with established and emerging leaders in all of these areas. The conference chairs have assembled a cutting-edge program that includes 36 leading scientists, all of whom have confirmed their attendance. In addition to invited oral presentations there will be several poster sessions. The conference program is available on-line at http://www.grc.org/programs.aspx?year=2011&program=gasphase). PUBLIC HEALTH RELEVANCE: New developments in medicine and public health in the 21st Century are likely to depend on an improved understanding of the structure, dynamics, and function of biological systems at the molecular level. The Gordon Research Conference on Biological Molecules in the Gas Phase and in Solution was created in 2001 to address this need. The 2011 meeting, the sixth in the series, will especially focus on identifying the frontier areas in biology that will benefit from collaborative research involving the biomolecular mass spectrometry, optical spectroscopy, and computational chemistry modeling communities.

描述（由申请人提供）：要求对戈登研究会议的支持，该会议将于2011年7月31日至8月5日在新罕布什尔州安多弗的普罗克特学院举行。这个戈登研究会议（GRC）将提供一个国际论坛，讨论与蛋白质，肽，核酸，碳水化合物和其他生命分子构建模块的结构和动力学相关的基本问题。本次会议的一个重点是通过质谱和相关方法（包括化学标记，离子迁移率和各种解离方法）表征生物分子。另一个重点是通过光谱工具询问生物分子系统。此外，会议将突出关键的计算和理论贡献。一些问题，将被解决包括以下内容：如何做生物分子的行为，一旦他们被剥夺了他们的水环境？如何利用气相方法来获得溶液中生物分子的结构信息？生物分子如何与水相互作用？生物分子在水以外的溶剂中是如何表现的？这次会议的独特性源于其强烈的跨学科性质，因为它汇集了在化学，生物学，物理学和医学界面工作的实验学家和理论家。该研讨会还为年轻科学家提供了一个与所有这些领域的成熟和新兴领导者互动的绝佳机会。会议主席已经组建了一个尖端计划，其中包括36位顶尖科学家，他们都已确认出席。除了应邀的口头介绍外，还将举行几次海报会议。会议日程可在http://www.grc.org/programs.aspx?网站上查阅年份= 2011年&程序=气相）。 公共卫生相关性：世纪医学和公共卫生的新发展很可能取决于在分子水平上对生物系统的结构、动力学和功能的更好理解。戈登研究会议的生物分子在气相和溶液中创建于2001年，以满足这一需求。2011年的会议是该系列会议的第六次，将特别关注确定生物学的前沿领域，这些领域将受益于涉及生物分子质谱、光学光谱和计算化学建模社区的合作研究。