2011 Biological Molecules in the Gas Phase and in Solution GRC

2011 气相和溶液中的生物分子 GRC

• 批准号: 8193187
• 负责人: DAVID E. CLEMMER
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-15 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8193187
• 关键词: Academy; Address; Area; Bioinformatics; Biological; Biology; Blood Circulation; Carbohydrates; Chemicals; Chemistry; Collaborations; Communities; Development; Dissociation; Environment; Funding; Future; Gases; Goals; Individual; International; Label; Life; Mass Spectrum Analysis; Medicine; Methods; Modeling; Molecular; New Hampshire; Optics; Oral; Participant; Peptide Nucleic Acids; Pharmacy facility; Phase; Physics; Play; Postdoctoral Fellow; Protein Dynamics; Proteomics; Public Health; Research; Research Personnel; Role; Scientist; Series; Solutions; Solvents; Spectrum Analysis; Structure; Students; Supplementation; System; Talents; Travel; United States National Institutes of Health; Water; Work; aqueous; biological systems; computational chemistry; frontier; improved; interest; ion mobility; meetings; novel strategies; posters; programs; stem; success; symposium; tool

DESCRIPTION (provided by applicant): Support is requested for the Gordon Research Conference on "Biological Molecules in the Gas Phase and in Solution", which will take place during the week of July 31 to August 5, 2011 at Proctor Academy, Andover, New Hampshire. This Gordon Research Conference (GRC) will provide an international forum for discussing fundamental questions related to the structure and dynamics of proteins, peptides, nucleic acids, carbohydrates, and other molecular building blocks of life. One focus of this meeting is the characterization of biological molecules by mass spectrometry and related approaches (including chemical labeling, ion mobility and various dissociation methods). Another emphasis is on the interrogation of biomolecular systems by spectroscopic tools. In addition, the conference will highlight key computational and theoretical contributions. Some of the issues that will be addressed include the following: How do biological molecules behave once they have been deprived of their aqueous environment? How can gas phase methods be employed for obtaining structural information on biological molecules in solution? How do biological molecules interact with water? How do biological molecules behave in solvents other than water? The uniqueness of this meeting stems from its strongly interdisciplinary character, as it brings together experimentalists and theorists working at the interface of chemistry, biology, physics, and medicine. This GRC also provides a perfect opportunity for young scientists to interact with established and emerging leaders in all of these areas. The conference chairs have assembled a cutting-edge program that includes 36 leading scientists, all of whom have confirmed their attendance. In addition to invited oral presentations there will be several poster sessions. The conference program is available on-line at http://www.grc.org/programs.aspx?year=2011&program=gasphase). PUBLIC HEALTH RELEVANCE: New developments in medicine and public health in the 21st Century are likely to depend on an improved understanding of the structure, dynamics, and function of biological systems at the molecular level. The Gordon Research Conference on Biological Molecules in the Gas Phase and in Solution was created in 2001 to address this need. The 2011 meeting, the sixth in the series, will especially focus on identifying the frontier areas in biology that will benefit from collaborative research involving the biomolecular mass spectrometry, optical spectroscopy, and computational chemistry modeling communities.

描述（由申请人提供）：请求参加戈登研究会议的“天然气阶段和解决方案中的生物分子”会议，该会议将于2011年7月31日至8月5日在新罕布什尔州安多佛市Proctor Academy举行。这次戈登研究会议（GRC）将提供一个国际论坛，讨论与蛋白质，肽，核酸，碳水化合物和其他分子构建基础有关的基本问题。这次会议的重点是通过质谱和相关方法（包括化学标记，离子迁移率和各种解离方法）对生物分子的表征。另一个重点是通过光谱工具对生物分子系统的询问。此外，会议将重点介绍关键的计算和理论贡献。将要解决的一些问题包括以下内容：一旦它们被剥夺了水性环境，生物分子如何表现？如何使用气相方法来获得有关溶液中生物分子的结构信息？生物分子如何与水相互作用？除水以外的溶剂中，生物分子如何表现？这次会议的独特性源于其强烈的跨学科特征，因为它汇集了在化学，生物学，物理学和医学界面上工作的实验家和理论家。该GRC还为年轻科学家提供了与所有这些领域的已建立和新兴领导者互动的绝佳机会。会议主席已经组建了一个尖端计划，其中包括36位主要科学家，他们都证实了他们的出席率。除了被邀请的口头演示外，还会有几个海报会议。会议程序可在http://www.grc.org/programs.aspx?year=2011&program = gasphase上在线上获得。 公共卫生相关性：21世纪医学和公共卫生方面的新发展可能取决于对分子水平生物系统的结构，动态和功能的了解。在2001年创建了气相和解决方案中的戈登生物分子研究会议，以满足这一需求。 2011年的会议是该系列的第六次会议，尤其将专注于确定生物学领域的边界领域，这些领域将受益于涉及生物分子质谱，光谱和计算化学建模社区的协作研究。