Dosing and Motor Learning in Children with an Injured Brain or Cerebral Palsy

描述（由申请人提供）：拟议的研究峰会的目的是促进大规模或多地点研究提案的发展，以解决脑损伤或脑瘫（CP）儿童干预（剂量）的有效频率，强度和持续时间的阈值，并提高儿科物理治疗师的研究能力。我们将邀请一个跨学科的研究人员（物理治疗师，基础和临床科学家），来自资助机构的代表和家长参加为期2.5天的密集智囊团。峰会的结构将是：提供与这些儿童及其家庭的现实世界关注并列的问题的理论科学概述，将概念与制定科学问题和方法的实际问题相结合，以探索剂量，并制定该领域第二代研究优先事项的行动计划。我们认为，对儿科物理治疗研究人员投入时间和培训将导致研究生产力的显着提高，并最终导致大脑受伤或CP儿童的护理和治疗。事实上，以前的首脑会议，使用这些方法是相当成功的。 公共卫生相关性：拟议的项目针对的是干预的一个关键和更紧迫的方面，这对治疗效果以及治疗如何影响残疾儿童的结果至关重要。它还针对物理治疗师研究人员，这是一个落后于儿科领域其他研究人员的群体。对干预剂量问题的跨学科方法以及对儿科物理治疗研究人员的时间和培训的投入不仅会导致研究生产力的显着提高，而且最终会导致大脑受伤或CP儿童的护理和治疗。

DESCRIPTION (provided by applicant): The purpose of the proposed research summit is to foster development of large scale or multi-site research proposals to address thresholds for effective frequency, intensity, and duration of interventions (dosing) for children with injured brains or cerebral palsy (CP) and to enhance the research capacity of pediatric physical therapists. We will invite an interdisciplinary cadre of researchers (physical therapists, basic- and clinical scientists), representatives from funding agencies, and parents to an intensive 2.5-day think-tank. The summit will be structured to: provide theoretical scientific overview of the problem juxtaposed with real-world concerns for these children and their families, integrate concepts with practical issues of formulating scientific questions and approaches to explore dosing, and develop action plans for second generation research priorities in this area. We theorize that investing time and training to pediatric physical therapy researchers will result in significant gains in research productivity and ultimately the care and treatment of children with injured brains or CP. Indeed previous summits, using these approaches have been quite successful. PUBLIC HEALTH RELEVANCE: The proposed project targets a critical and more pressing aspect of intervention that is pivotal to treatment efficacy and how treatments influence outcome in children with disabilities. It also targets physical therapist researchers, a group that lags behind other researchers in the area of pediatrics. The interdisciplinary approach to the problems of dosing of interventions and investing time and training to pediatric physical therapy researchers will not only result in significant gains in research productivity, but also ultimately in the care and treatment of children with injured brains or CP.