7th World Congress on Developmental Origins of Health and Disease - NIH

第七届健康与疾病发展起源世界大会 - NIH

• 批准号: 8130178
• 负责人: Susan P Bagby
• 金额: $ 2.3万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8130178
• 关键词: Adolescence; Adult; Age; Aging; American; Atherosclerosis; Attenuated; Award; Barker Hypothesis; Basic Science; Cardiovascular Diseases; Caring; Child; Chronic Disease; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communication; Communities; Congresses; Developing Countries; Development; Diabetes Mellitus; Diet; Dietary Intervention; Disabled Persons; Discipline; Disease; Elderly; Ensure; Environment; Epidemic; Epidemiologist; Event; Family; Fetal Development; Fostering; Functional disorder; Funding; Future; Future Generations; Goals; Grant; Growth; Habits; Health; Health Care Costs; Health Personnel; Health Policy; Health Professional; Heart Diseases; Human Resources; Hypersensitivity; Hypertension; Incidence; Infant; International; Intervention Trial; Investigation; Journals; Knowledge; Lead; Life; Link; Long-Term Effects; Malignant Neoplasms; Malnutrition; Medical; Mental disorders; Mentors; Metabolic; Metabolic Diseases; Mind; Minority; Mission; Mothers; Nutritional; Nutritional Support; Obesity; Oral; Oregon; Outcome; Overnutrition; Peer Review; Perinatal; Plant Roots; Policy Maker; Population; Pregnant Women; Process; Provider; Public Health; Public Policy; Publishing; Request for Applications; Research; Research Personnel; Risk; Scientist; Societies; Stress; Time; Toxicant exposure; Translating; Travel; United States National Institutes of Health; Woman; abstracting; base; burden of illness; career; child bearing; clinical practice; cost; developmental nutrition; fitness; girls; improved; in utero; member; multidisciplinary; novel; nutrition; offspring; pediatrician; posters; postnatal; pregnant; prenatal; prevent; programs; reproductive; social; stressor; success; symposium; transmission process

DESCRIPTION (provided by applicant): The field of developmental programming has rapidly expanded in the two decades since David Barker described a relationship between poor in utero growth and increased vulnerability for chronic disease in adulthood. We now know that sub-optimal conditions (eg under- or overnutrition, stress) during critical windows in the periconceptional, gestational, and perinatal periods interact with postnatal factors (including diet) to amplify the risk for developing chronic diseases in adulthood; these include obesity, heart disease, diabetes and cancer. The 7th World Congress on Developmental Origins of Health and Disease (DOHaD) will be held in Portland, OR, USA on September 18-21, 2011. This will be the first time this Congress has been held in the US and represents a unique opportunity for US scientists, clinicians and policy makers to participate in discussions with key personnel in this worldwide field. Since the inception of the International DOHaD Society in 2003, there has been an underrepresentation of US members despite several leading experts in the field being based in the US; we thus anticipate increased US participation at the 7th World Congress on DOHaD. Deliberate inclusion of sessions geared towards changing clinical practice and public health policies is a novel feature of the 7th World Congress and could have major impacts on improving adult health worldwide, in addition to substantial reductions in the health care costs associated with chronic disease. This biennial multidisciplinary World Congress is being organized with several goals in mind: (a) to disseminate the results from the most recent mechanistic and interventional studies, (b) to bring together, and stimulate discussion between experts in this broad field, (c) to facilitate interactions between basic scientists, clinicians, and health policy makers regarding best practice in preventing or attenuating the long-term negative effects of a sub-optimal intrauterine environment. This Congress will also provide a key opportunity to further understanding in the field of developmental programming and identify scientific gaps in knowledge. A longstanding emphasis of the DOHaD Society has been to promote attendance of junior investigators, minorities, and delegates from developing nations and this continues for the 7th World Congress; merit-based travel grants will be available to these groups. Mentoring luncheons, a social mixer and a Junior Investigator Award session have been organized to foster interactions amongst early career researchers and initiate collaborations and contacts that are so critical for long term career success in research. The Congress program comprises over 50 invited speakers (plenary and parallel sessions), and oral and poster presentations of peer-reviewed abstract submissions. Abstracts will be published in the Journal of DOHaD, available during and after the congress. The ability to bring together researchers, health care workers and policy makers promotes communication between these often disparate groups and will increase the likelihood of solving many of the important issues associated with developmental programming and health. PUBLIC HEALTH RELEVANCE: Both undernutrition and overnutrition/obesity in pregnant mothers - dual forms of malnutrition - negatively impact fetal development with long-term effects to increase vulnerability for common chronic diseases: hypertension, cardiovascular disease, obesity, and diabetes. The escalating worldwide obesity epidemic, leading to obesity in girls and mothers-to-be, sets up a vicious cycle with trans-generational transmission of obesity and metabolic dysfunction. This multi-disciplinary congress will facilitate interactions and discussions between scientists, clinicians and public health policy makers to initiate key changes in care for women who are pregnant or of child bearing age, with a goal of improve the long-term health of their offspring.

描述（由申请人提供）：自从David Barker描述了子宫内发育不良与成年后易患慢性病之间的关系以来，发展规划领域在20年内迅速扩大。我们现在知道，在围孕期、妊娠期和围产期的关键时期，次优条件（如营养不足或营养过剩、压力）与产后因素（包括饮食）相互作用，增加了成年后患慢性病的风险；这些疾病包括肥胖、心脏病、糖尿病和癌症。第七届世界健康与疾病发展起源大会将于2011年9月18日至21日在美国俄勒冈州波特兰举行。这将是该大会首次在美国举行，为美国科学家、临床医生和政策制定者提供了一个独特的机会，与这一全球领域的关键人员进行讨论。自2003年国际DOHaD协会成立以来，尽管该领域的几位顶尖专家都在美国，但美国成员的代表性一直不足；因此，我们预计美国将更多地参加第七届世界人道主义问题大会。有意纳入旨在改变临床实践和公共卫生政策的会议是第七届世界大会的一个新特点，除了大幅降低与慢性病有关的卫生保健费用外，还可能对改善全世界成人健康产生重大影响。举办这个两年一次的多学科世界大会，考虑到以下几个目标：(a)传播最新的机械和介入研究结果；(b)汇集并促进这一广泛领域专家之间的讨论；(c)促进基础科学家、临床医生和卫生决策者之间就预防或减轻次优宫内环境长期负面影响的最佳做法进行互动。本次大会还将为进一步了解发展规划领域和确定科学知识差距提供重要机会。DOHaD协会长期以来的重点是促进来自发展中国家的初级调查人员、少数民族和代表的出席，这在第七届世界大会上仍在继续；这些团体将获得基于成绩的旅行补助金。组织了指导午餐会、社交酒会和青年研究者奖会议，以促进早期职业研究人员之间的互动，并启动对长期职业研究成功至关重要的合作和联系。大会计划包括50多位受邀演讲者（全体会议和平行会议），以及经同行评审的摘要提交的口头和海报演讲。会议摘要将发表在《DOHaD杂志》上，在大会期间和会议结束后提供。将研究人员、卫生保健工作者和决策者聚集在一起的能力促进了这些往往不同的群体之间的交流，并将增加解决与发展规划和卫生有关的许多重要问题的可能性。