Training in Neural Injury and Plasticity

描述(由申请人提供)：项目摘要/摘要这是一份神经损伤和可塑性机构培训补助金(NIP)的竞争性续期申请。我们请求为4名高级博士后学生提供支持，他们将接受乔治敦大学神经损伤和恢复中心(CNIR)的神经损伤和可塑性研究培训。本培训计划的目的是让科学家做好准备，研究创伤、中风或神经退行性过程造成的神经损伤的基本机制，并了解神经可塑性的基本机制，这些机制可能在功能上有利于神经损伤后的修复过程。我们的目标是培养能够并致力于开发新的有效治疗策略的基础科学部分的研究人员，以减少神经损伤造成的功能损伤。一个经验丰富、资金充足的27名教职员工将参加博士培训计划，他们在神经损伤和可塑性方面具有广泛的研究兴趣和专业知识。学生将通过乔治城大学神经科学跨学科项目(IPN)进入研究生院。在头两年，他们将参加课程作业，并轮流在潜在导师的实验室中轮换。那些对NIP计划感兴趣的人将参加一个或多个具体相关的课程，开始参加NIP期刊俱乐部，并与一群杰出的临床医生和科学家一起获得临床经验，以提供 基础科学家，了解患者和临床医生处理神经损伤和可塑性的经验。在第二年，学生将正式申请NIP培训计划，并由NIP培训学院的潜在导师或合作导师批准论文研究计划的大纲。作为NIP学员，他们将参加每周NIP期刊俱乐部以及CNIR的教育方案，并计划在每年的学生研讨会上报告他们的研究结果，在全国会议上发表演讲，并在同行评议的期刊上发表文章。在公共卫生方面，该方案将培养一支经过研究和/或研究方案管理培训的神经科学家队伍，通过他们可以治疗急性和退行性神经系统疾病的新的、更有效的治疗方法。 公共卫生相关性：项目描述本研究培训计划的重点是高级博士后学生在神经损伤和对损伤的反应方面的发展。在公共卫生方面，该计划将培养一支研究和/或研究项目管理的神经科学家队伍，通过他们可以治疗急性和退行性神经系统疾病的新的、更有效的治疗方法。

DESCRIPTION (provided by applicant): Project Summary/Abstract This is an application for the competitive renewal of an Institutional Training Grant in Neural Injury and Plasticity (NIP). We request support for 4 advanced predoctoral students who will be trained in research on neural injury and plasticity by faculty participating in the Center for Neural Injury and Recovery (CNIR) at Georgetown University. The purpose of this training program is to prepare scientists to investigate fundamental mechanisms of neural injury, by trauma, stroke or neurodegenerative processes and to understand basic mechanisms of neural plasticity that may be functionally beneficial to the repair processes after neural injury. Our goal is to train researchers who will b capable of and committed to the basic science component of developing novel and effective treatment strategies to reduce the functional impairments that result from neural injury. An experienced and well-funded group of 27 faculty members with a wide range of research interests and expertise in neural injury and plasticity will participate in the Ph.D. training program. Students will enter graduate school through the Georgetown University Interdisciplinary Program in Neuroscience (IPN). In the first two years they will take course work and rotate through the laboratories of potential mentors. Those interested in the NIP Program will take one or more specifically relevant courses, begin to participate in the NIP Journal Club and also obtain a clinical experience with an outstanding group of clinician-scientists, to provide basic scientists with an appreciation of the experiences of patients and clinicians dealing with neural injury and plasticity. In the second year, students will formally apply to the NIP Training Program with the outline of a thesis research proposal approved by a potential mentor or co-mentors from the NIP Training Faculty. As NIP Trainees they will participate in the weekly NIP Journal Club as well as educational programs of the CNIR and plan to report results from their research in yearly student seminars, presentations at national meetings and as publications in peer reviewed journals. With respect to public health, this program will create a cadre of neuroscientists trained for research and/or management of research programs, through which new and more effective treatments for acute and degenerative disorders of the nervous system can be treated. PUBLIC HEALTH RELEVANCE: Project Narrative This research training program is focused on the development of advanced predoctoral students in the area of neural injury and responses to injury. With respect to public health, this program will create a cadre of neuroscientists traind for research and/or management of research programs, through which new and more effective treatments for acute and degenerative disorders of the nervous system can be treated.