Neural Injury and Plasticity Training Program

项目总结/摘要 这是一份神经损伤机构培训补助金竞争性续期的申请， 可塑性（NIP）。我们请求支持4名高级博士生，他们将接受以下方面的研究培训 神经损伤和可塑性的教师参加中心神经损伤和恢复（CNIR）在 乔治敦大学。这个培训项目的目的是让科学家们做好调查的准备 神经损伤的基本机制，由创伤，中风或神经退行性过程， 了解神经可塑性的基本机制，可能在功能上有利于修复过程 神经损伤后。我们的目标是培养能够并致力于基础科学的研究人员 开发新的和有效的治疗策略的组成部分，以减少功能障碍， 是神经损伤造成的一个经验丰富，资金充足的20名教师组成的小组，具有广泛的 在神经损伤和可塑性的研究兴趣和专业知识将参加博士学位。培训计划。 大多数学生将通过乔治敦大学跨学科项目进入研究生院， 神经科学（IPN）。在最初的两年里，他们将参加课程工作，并在以下实验室轮换： 潜在的导师对NIP计划感兴趣的人将参加一个或多个具体相关的课程， 开始参加NIP期刊俱乐部。在第二年，学生将正式申请NIP 培训计划，由潜在导师或共同导师批准的论文研究计划大纲 从NIP培训学院。作为NIP学员，他们将参加NIP特定培训，其中包括： 与一群杰出的临床医生-科学家的临床经验，为基础科学家提供 对处理神经损伤和可塑性的患者和临床医生的经验的赞赏;每周 NIP期刊俱乐部和扩展的综合推理和统计素养培训;专业发展 训练（即，电梯推销，赠款写作和演讲技巧，有效的沟通技巧）以及 每月的会议集中于深入讨论神经损伤和可塑性特有的疾病。学员 将在每年的学生研讨会上报告他们的研究结果，在国家会议上发表演讲， 在同行评审期刊上发表文章。在公共卫生方面，该方案将建立一个 神经科学家培训的研究和/或管理的研究计划，通过新的和更多的 可以开发出对神经系统的急性和变性疾病的有效治疗。

Project Summary/Abstract This is an application for the competitive renewal of an Institutional Training Grant in Neural Injury and Plasticity (NIP). We request support for 4 advanced predoctoral students who will be trained in research on neural injury and plasticity by faculty participating in the Center for Neural Injury and Recovery (CNIR) at Georgetown University. The purpose of this training program is to prepare scientists to investigate fundamental mechanisms of neural injury, by trauma, stroke or neurodegenerative processes and to understand basic mechanisms of neural plasticity that may be functionally beneficial to the repair processes after neural injury. Our goal is to train researchers who will be capable of and committed to the basic science component of developing novel and effective treatment strategies to reduce the functional impairments that result from neural injury. An experienced and well-funded group of 20 faculty members with a wide range of research interests and expertise in neural injury and plasticity will participate in the Ph.D. training program. Most students will enter graduate school through the Georgetown University Interdisciplinary Program in Neuroscience (IPN). In the first two years they will take course work and rotate through the laboratories of potential mentors. Those interested in the NIP Program will take one or more specifically relevant courses and begin to participate in the NIP Journal Club. In the second year, students will formally apply to the NIP Training Program with the outline of a thesis research proposal approved by a potential mentor or co-mentors from the NIP Training Faculty. As NIP Trainees they will participate in NIP Specific Training which includes: clinical experience with an outstanding group of clinician-scientists, to provide basic scientists with an appreciation of the experiences of patients and clinicians dealing with neural injury and plasticity; the weekly NIP Journal Club and extended integrative reasoning and statistical literacy training; professional development training (i.e., Elevator pitches, grant writing and presentation skills, effective communication skills) as well as monthly meetings focused on in-depth discussions of disorders specific to neural injury and plasticity. Trainees will report results from their research in yearly student seminars, presentations at national meetings, and as publications in peer-reviewed journals. With respect to public health, this program will create a cadre of neuroscientists trained for research and/or management of research programs, through which new and more effective treatments for acute and degenerative disorders of the nervous system can develop.