Neural Injury and Plasticity Training Program

项目摘要/摘要 这是一份竞争续签神经损伤和医疗机构培训补助金的申请。 塑性(NIP)。我们请求支持4名高级博士后，他们将在研究方面接受培训 神经损伤和恢复中心(CNIR)教职员工的神经损伤和可塑性 乔治城大学。该培训计划的目的是为科学家进行调查做好准备 神经损伤的基本机制，通过创伤、中风或神经退行性过程以及 了解神经可塑性的基本机制，这可能在功能上有利于修复过程 在神经损伤之后。我们的目标是培养有能力并致力于基础科学的研究人员 开发新的和有效的治疗策略的组成部分，以减少 是神经损伤造成的。一个由20名教职员工组成的经验丰富且资金充足的团队，他们拥有广泛的 神经损伤和可塑性方面的研究兴趣和专业知识将参与博士培训计划。 大多数学生将通过乔治敦大学跨学科项目进入研究生院 神经科学(IPN)。在头两年，他们将参加课程作业，并轮流在 潜在的导师。对NIP方案感兴趣的人将参加一门或多门具体相关的课程，并 开始参加NIP期刊俱乐部。在第二年，学生将正式申请加入新高中。 培训计划，其中包含潜在导师或共同导师批准的论文研究计划大纲 来自NIP培训学院。作为NIP学员，他们将参加NIP专门培训，其中包括： 拥有一批优秀的临床医生和科学家的临床经验，为基础科学家提供 评价患者和临床医生处理神经损伤和可塑性的经验 NIP期刊俱乐部和扩展的综合推理和统计素养培训；专业发展 培训(即电梯推介、助学金写作和演示技能、有效沟通技能)以及 每月会议的重点是深入讨论特定于神经损伤和可塑性的疾病。实习生 将在每年的学生研讨会上报告他们的研究结果，在全国会议上发表演讲，以及 在同行评议的期刊上发表文章。在公共卫生方面，该计划将培养一支 神经科学家接受了研究和/或研究项目管理的培训，通过这些项目，新的和更多的 可以开发出治疗急性和退行性神经系统疾病的有效方法。

Project Summary/Abstract This is an application for the competitive renewal of an Institutional Training Grant in Neural Injury and Plasticity (NIP). We request support for 4 advanced predoctoral students who will be trained in research on neural injury and plasticity by faculty participating in the Center for Neural Injury and Recovery (CNIR) at Georgetown University. The purpose of this training program is to prepare scientists to investigate fundamental mechanisms of neural injury, by trauma, stroke or neurodegenerative processes and to understand basic mechanisms of neural plasticity that may be functionally beneficial to the repair processes after neural injury. Our goal is to train researchers who will be capable of and committed to the basic science component of developing novel and effective treatment strategies to reduce the functional impairments that result from neural injury. An experienced and well-funded group of 20 faculty members with a wide range of research interests and expertise in neural injury and plasticity will participate in the Ph.D. training program. Most students will enter graduate school through the Georgetown University Interdisciplinary Program in Neuroscience (IPN). In the first two years they will take course work and rotate through the laboratories of potential mentors. Those interested in the NIP Program will take one or more specifically relevant courses and begin to participate in the NIP Journal Club. In the second year, students will formally apply to the NIP Training Program with the outline of a thesis research proposal approved by a potential mentor or co-mentors from the NIP Training Faculty. As NIP Trainees they will participate in NIP Specific Training which includes: clinical experience with an outstanding group of clinician-scientists, to provide basic scientists with an appreciation of the experiences of patients and clinicians dealing with neural injury and plasticity; the weekly NIP Journal Club and extended integrative reasoning and statistical literacy training; professional development training (i.e., Elevator pitches, grant writing and presentation skills, effective communication skills) as well as monthly meetings focused on in-depth discussions of disorders specific to neural injury and plasticity. Trainees will report results from their research in yearly student seminars, presentations at national meetings, and as publications in peer-reviewed journals. With respect to public health, this program will create a cadre of neuroscientists trained for research and/or management of research programs, through which new and more effective treatments for acute and degenerative disorders of the nervous system can develop.