Midwest Blood Club Symposium, 2012

中西部血液俱乐部研讨会，2012 年

• 批准号: 8319059
• 负责人: REBECCA J. CHAN
• 金额: $ 0.5万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8319059
• 关键词: Allogenic; Anemia; Area; Autologous; Basic Science; Blood; Blood Cells; Chronic Myeloid Leukemia; Coagulation Process; Collaborations; Congenital Disorders; Data; Diagnosis; Disease; Environment; Etiology; Extramural Activities; Fostering; Functional disorder; Hematologic Neoplasms; Hematological Disease; Hematopoiesis; Hematopoietic; Hematopoietic stem cells; Hemorrhage; Hospitalization; Human Resources; Indiana; Individual; Infection; Institution; Kentucky; Malignant Neoplasms; Measures; Morbidity - disease rate; Myeloproliferative disease; Office Visits; Ohio; Outcomes Research; Oxygen; Patient Care; Patients; Physicians; Physiological; Postdoctoral Fellow; Preventive; Productivity; Research; Research Personnel; Scientist; Services; Solid; Stem cell transplant; Tissues; Training; Translational Research; United States; Universities; Washington; Wisconsin; Yang; base; clinically significant; fighting; graduate student; improved; interest; leukemia; medical schools; meetings; microcytic/hypochromic anemia; mortality; peripheral blood; planetary Atmosphere; posters; stem cell biology; symposium

DESCRIPTION (provided by applicant): The blood is a specialized tissue that performs several crucial physiologic functions including carrying oxygen, fighting infections, and clotting wounds. The etiology of blood cell dysfunction is diverse and results in a myriad of blood disorders including anemia, myeloproliferative disorder, leukemia, infections, bleeding disorders, and hypercoagulable states. Despite considerable advances in the diagnosis and treatment of blood disorders, these diseases continue to cause significant patient morbidity and mortality. Additionally, autologous and allogeneic stem cell transplantation continues to be a mainstay of therapy for several congenital disorders and acquired malignancies. Thus, collectively, improved understanding of normal hematopoiesis, stem cell biology, and hematopoietic disease states is relevant to our national interest in the United States in terms of preventive measures and improved therapies for blood disorders, congenital disorders, and cancers. The Midwest Blood Club Symposium was initiated in 2003 as a forum to facilitate collaborative ties between investigators at Midwestern universities with a mutual interest in hematopoiesis and hematopoietic stem cell biology. The objectives of this meeting have been to foster regional collaborations in the area of hematopoiesis and stem cell biology within the Midwest and to provide a collegial atmosphere for the training of graduate students and post-doctoral fellows in platform and poster presentations. As we move forward, we are seeking to attract more physician scientists involved in both patient care and basic research, in an effort to underscore the clinical significance and potential application of the basic science studies traditionally presented at this meeting. By meeting on an annual basis, investigators can harness strengths of collaborating colleagues and institutions, resulting in a synergistic increase in productivity. Because of these inter-institutional interactions and collaborations, institutional and extramural research dollars are more efficiently utilized and leveraged for high quality research outcomes. We aim to 1) provide a venue for dialogue of ideas and exchange of expertise and services among investigators located in the Midwest focused on hematopoiesis and hematopoietic stem cell biology; 2) engender an amiable, yet challenging, environment to educate and train graduate students and post-doctoral fellows in the presentation, explanation, and justification of scientific data and interpretation; and 3) broaden the scope of the meeting to include more physician scientists to provide context and perspective on the significance of the ongoing basic science studies and to present clinically-based studies.

描述（由申请人提供）：血液是一种特殊的组织，具有几种重要的生理功能，包括携带氧气、抵抗感染和凝血伤口。血细胞功能障碍的病因是多种多样的，并导致无数的血液疾病，包括贫血、骨髓增生性疾病、白血病、感染、出血性疾病和高凝状态。尽管在血液疾病的诊断和治疗方面取得了相当大的进展，但这些疾病继续导致显著的患者发病率和死亡率。此外，自体和同种异体干细胞移植仍然是几种先天性疾病和获得性恶性肿瘤的主要治疗方法。因此，总的来说，改善对正常造血、干细胞生物学和造血疾病状态的理解，在预防措施和改善血液疾病、先天性疾病和癌症的治疗方面，与我们在美国的国家利益有关。中西部血液俱乐部研讨会于2003年发起，作为一个论坛，以促进在造血和造血干细胞生物学共同感兴趣的中西部大学的研究人员之间的合作关系。本次会议的目标是促进区域合作，在造血和干细胞生物学领域内的中西部，并提供一个学院的氛围，为研究生和博士后研究员的培训平台和海报演示。随着我们的前进，我们正在寻求吸引更多的医生科学家参与患者护理和基础研究，以强调传统上在本次会议上提出的基础科学研究的临床意义和潜在应用。通过每年举行会议，研究人员可以利用合作同事和机构的优势，从而协同提高生产力。由于这些机构间的互动和合作，机构和校外的研究资金得到更有效的利用和杠杆高质量的研究成果。我们的目标是：1）为位于中西部的造血和造血干细胞生物学研究人员提供一个思想对话和专业知识和服务交流的场所; 2）创造一个友好但具有挑战性的环境，以教育和培训研究生和博士后研究员，介绍，解释和科学数据和解释的理由; 3）扩大会议范围，包括更多的医生科学家，以提供正在进行的基础科学研究的意义的背景和观点，并提出临床为基础的研究。