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中文摘要
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摘要: 在拉美裔人口中,癌症发病率、死亡率和发病率方面的差异仍然存在。癌症是波多黎各(PR)的第二大死因,但该岛的癌症研究意识和机会仍然有限。在全国范围内,专注于癌症的拉美裔教师仍然很少,包括波多黎各人、临床和基础科学教师。这对缩小拉美裔人口健康差距方面的进展产生了负面影响。庞塞医学院/莫菲特癌症中心(PSM/MCC)合作伙伴关系的培训/职业发展核心的总体长期目标是增加基础科学研究人员和临床研究科学家的数量和成功,重点是加强PR人群的癌症研究。这一培训核心将通过提高未被充分代表的少数族裔学生和服务于这些群体的学生的学术、研究和专业能力来实现这些目标。培训/职业发展核心的具体可衡量目标如下:(1)为PSM的博士生建立癌症研究轨道,以增加基础科学癌症研究人员的数量,并加强以波多黎各人口为重点的癌症研究;(2)建立医学生和研究员的临床培训渠道,以加强PR人群的临床癌症、研究和治疗;(3)加强伙伴关系初级调查人员的职业发展。为了实现这些目标,我们将吸引波多黎各的早期职业博士研究生,让他们沉浸在癌症研究环境中。MCC癌症中心博士生的互惠研究交流和综合健康差异教育将建立一个强大的基础科学家网络,以解决癌症差异问题。第二,我们将为PSM医学生建立肿瘤学轨道。第三,这个核心将支持岛上肿瘤学研究员独特的临床研究培训体验。这一新的肿瘤学奖学金计划将在MCC、PSM、圣胡安VA医疗医院和圣胡安市医院提供临床试验和转化研究方面的协调培训。第四,核心将支持伙伴关系教员学员的职业发展计划,以建设PSM的研究能力。通过共享发展讲习班和长期互动,使受训人员和初级教员建立联系,将使受训人员充分融合,并支持在岛上建立成功的癌症研究事业。对受训者和初级教师指导对象的职业道路进行严格评估和跟踪,将评估计划的有效性,并为改进核心的教育和培训部分提供反馈。这些目标的成功成果将增加波多黎各癌症研究人员的数量和成就,促进PSM的长期癌症研究培训基础设施,并加强旨在改善波多黎各和佛罗里达州拉美裔人口癌症诊断和治疗的癌症研究。培训/职业发展核心将补充和利用MCC和PSM的现有计划,通过提供训练有素的劳动力来开展与癌症相关的研究,并创造新的研究计划,以解决拉美裔人口中发现的健康差距,从而显著增强总体伙伴关系目标。
英文摘要
ABSTRACT: Disparities in cancer incidence, mortality and morbidity continue to exist within the Hispanic population. Cancer is the second leading cause of death in Puerto Rico (PR), yet cancer research awareness and opportunities remain somewhat limited on the Island. Nationwide there continues to be a paucity of Hispanic, including Puerto Rican, clinical and basic science faculty with a focus on cancer. This negatively impacts progress in reducing health disparities in the Hispanic population. The overall long-term objective of the Training/Career Development Core of the Ponce School of Medicine/Moffitt Cancer Center (PSM/MCC) Partnership is to increase the numbers and success of basic science investigators and clinical research scientists focused on enhancing cancer research for the PR population. This training core will accomplish these goals through enhancement of the academic, research, and professional competence of both the underrepresented minority students and those serving these populations. The specific measurable objectives of the Training/Career Development Core are as follows: (1) to build a cancer research track for Ph.D. students at PSM to increase the number of basic science cancer investigators and enhance cancer research focused on the Puerto Rican population; (2) to build a clinical training pipeline of medical students and fellows to enhance clinical cancer, research and treatment of the PR population; and (3) to enhance career development of partnership junior investigators. To achieve these objectives we will capture early career PhD graduate students in Puerto Rico, immersing them in a cancer research environment. A reciprocal research exchange of PhD students from the MCC Cancer Center and integrated health disparities education will develop a strong network of basic scientists to address cancer disparities issues. Second, we will establish an oncology track for PSM medical students. Third, this Core will support a unique clinical research training experience for oncology fellows on the island. This novel oncology fellowship program will provide coordinated training in clinical trials and translational research at MCC, PSM, San Juan VA Medical Hospital and San Juan City Hospital. Fourth, the Core will support the career development plans of the Partnership faculty mentees to build research capacity at PSM. Networking of the trainees and junior faculty through shared developmental workshops and long-term interactions will fully integrate the trainees and support establishment of successful cancer research careers on the island. Critical evaluation and tracking of the career paths of the trainees and junior faculty mentees will assess program effectiveness, and provide feedback for improving the education and training components of the Core. Successful outcomes from these goals will enhance the numbers and achievements of Puerto Rican cancer investigators, contribute to a long-term cancer research training infrastructure at PSM, and augment cancer research aimed at improving the diagnosis and treatment of cancer in the Hispanic population in both Puerto Rico and Florida. The Training/Career Development Core will complement and leverage the existing programs at both MCC and PSM to significantly enhance the overall Partnership objectives by providing a better trained workforce to conduct cancer related research with the momentum to create new research initiatives addressing the health disparities found in Hispanic populations.
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The Enteric Glia as a Possible Target for Symptom Relief in Endometriosis
  • 批准号:
    10625609
  • 项目类别:
  • 资助金额:
    $15.68万
  • 财政年份:
    2023
  • 负责人:
    Caroline B Appleyard
  • 依托单位:
Repurposing CRH antagonists for the treatment of endometriosis
  • 批准号:
    10746682
  • 项目类别:
  • 资助金额:
    $7.12万
  • 财政年份:
    2023
  • 负责人:
    Caroline B Appleyard
  • 依托单位:
Repurposing CRH antagonists for the treatment of endometriosis
  • 批准号:
    10602801
  • 项目类别:
  • 资助金额:
    $29.99万
  • 财政年份:
    2022
  • 负责人:
    Caroline B Appleyard
  • 依托单位:
G-RISE at Ponce Health Sciences University
  • 批准号:
    10360344
  • 项目类别:
  • 资助金额:
    $63.7万
  • 财政年份:
    2022
  • 负责人:
    Caroline B Appleyard
  • 依托单位:
海外基金