Training Grant in Cardiac and Vascular Cell Biology

该培训计划为博士后和博士后学员提供高质量的跨学科培训体验 心血管生理学和病理生理学。培训包括分子、细胞和系统生物学，以及 强调翻译科学。我们的目标是为学员提供全面、多方面的心脏培训 和血管细胞生物学，充满了对疾病相关性的强烈赞赏，他们的研究。我们的32名教职员工 导师来自护理学院医学院(SOM)的13个基础和临床科 (SON)和马里兰大学生物技术研究所的医学生物技术中心(MBC)。全 高级教员导师由NIH资助；我们有才华的新初级教员本身受到密切指导，为他们提供 培训计划的下一波导师该计划将精选的、有积极性的学生和 博士后研究员。培训机会广泛，包括：心血管功能的分子决定因素， 心脏和血管信号通路的结构和功能研究，包括蛋白质运输。在这次更新中 心血管疾病的遗传学，个体心脏和心脏功能的分析，以及 血管细胞，以及整个组织和完整器官的生物力学特性。通过重组 在生命科学研究生课程(GPILS)下的医学院(SOM)研究生课程， TGE博士前申请者的质量和数量继续增加。对研究生教育的机构支持是 出类拔萃，年投资超过200万美元。GPILS还带头指导博士后研究员(例如 职业研讨会、赠款撰写讲习班)。博士前实习生的课程由8学分组成 课程，肌肉生物学、分子生物学和功能基因组学的跨学科课程。中的主题 分子医学，心脏病理生理学的新课程和心血管方面的实践课程 本能。该计划为跨学科的博士后和博士后互动社区提供了框架 实习生。博士后研究员参加两个心血管强化课程的学分，并加入博士后实习生在 定期举行会议，介绍正在进行的工作，提供对计划的反馈，出席并在每周午餐时间介绍情况 研究论坛，每周一次的期刊俱乐部和年度研究务虚会。新的计划总监和新的指导 委员会和一个外部咨询委员会(选管会)密切跟踪学员的进展情况和 整体计划。完成这项计划的学员将准备好运用一系列的实验方法 关于正常心脏和血管细胞生物学中的基本问题，关于心脏疾病的潜在机制 和血管病理，以及它们可能的治疗和预防。 相关性(请参阅说明)：

This Training Program provides a high-quality interdisciplinary training experience for pre- and postdoctoral trainees in cardiovascular physiology and pathophysiology. Training includes molecular, cell and systems biology, with an emphasis on translational science. Our goal is to provide trainees with comprehensive, multi-faceted training in cardiac and vascular cell biology, imbued with a strong appreciation of the disease relevance of their research. Our 32 faculty mentors are from 13 basic and clinical departments and divisions in the School of Medicine (SOM), School of Nursing (SON) and Medical Biotechnology Center (MBC) of the University of Maryland Biotechnology Institute (UMBI). All senior faculty mentors are NIH-funded; our talented new junior faculty, are, themselves, closely mentored provide the next wave of mentors for the Training Program The Program brings together selected, motivated students and postdoctoral fellows. Training opportunities are broad and include: molecular determinants of cardiovascular function, structure and function studies of cardiac and vascular signaling pathways, including protein trafficking. In this renewal there is increased focus, on genetics of cardiovascular diseases, analysis of the function of individual cardiac and vascular cells, as well as the biomechanical properties of whole tissues and intact organs. With reorganization of graduate studies at the School of Medicine (SOM) under the umbrella Graduate Program in Life Sciences (GPILS), quality and number of TGE predoctoral applicants continues to increase. Institutional support for graduate education is outstanding, with an annual investment over $2M. GPILS also takes the lead in mentoring postdoctoral fellows (e.g. career seminars, grant writing workshops). The coursework for pre-doctoral trainees consists of an 8 credit Core Curriculum, interdisciplinary courses in muscle biology, molecular biology and functional genomics. Topics in Molecular Medicine, a newly plaimed course on cardiac pathophysiology, and a hands on course on cardiovascular fiinction. The Program provides the framework for a cross-discipline, interactive community of pre- and postdoctoral trainees. Postdoctoral fellows take two cardiovascular intensive courses for credit and join with predoctoral trainees in regular meetings to present work-in-progress, provide feedback on the program, attend and present at weekly lunch time research forums, a weekly journal clubs and Annual Research Retreat. A new Program Director, and new Steering Committee, and an External Advisory Committee (EAC) closely track progress of the trainees and the success of the overall Program. Trainees completing this program will be prepared to bring to bear a range of experimental approaches on basic questions in normal cardiac and vascular cell biology, on the underlying mechanisms responsible for cardiac and vascular pathologies, and on their possible cure and prevention. RELEVANCE (See instructions):