C1 - Administrative Core

为该核心计划的工作是以 PPG的前一阶段，以实现高生产力和有效的整合。这个核心是PPG的一个枢纽 活动，并提供行政支持和指导，而不微观管理个别项目团队。 核心小组将负责定期安排、组织、主办和/或促进 支持PPG进展的会议。这些会议包括（一）-全体会议（包括 （二）-电子会议，（三）-方案规划小组参与促成的研究小组专题会议 参加国家和国际会议。核心负责差旅管理 支持这些会议，包括资金的分配和核算。核心保证 遵守所有机构、政府和NIH特定法规和要求，包括 及时与NIH沟通，并向NIH报告进展。所有财务报告和协调 包括国内外几个主要机构的PPG方面也得到了管理 通过核心活动。其他管理目标是确保以下决策 资源分配（和重新分配）、项目预期和进度，以及实现 以适当、公平、深思熟虑和及时方式处理项目、预算和支出问题。因此，核心将 继续发挥作用，以确保PPG的科学发现和传播的最大可能的影响。 （l）提供必要的监督、协调和行政支助， （2）在合同中约定的期限内，对合同的效力和履行情况进行审查。 PPG的计算生物学和生物信息学方面，包括资源共享和共享 （3）发展一套资讯管理系统， 以PPG为代表的研究领域的系统，包括计算机辅助专家 注释系统TRANSPORT注释中心（TRAC）和相关的文献挖掘工具 耦合器。 相关性（参见说明）： 我们研究了一套复杂的细胞机器和功能，在一个协调的科学努力，了解 这些机制对维持人类健康和防治疾病，如药物滥用至关重要。带 这些努力以有效和协调的方式结合在一起，我们利用行政核心， 科学研究的最高标准，遵守所有规则和条例，并分享 资源和拉腊埃财团和社区内的成果

The efforts planned for this Core, are modeled on the components that have been demonstrated in the previous period of the PPG to enable high productivity and efficient integration. This core is a hub of PPG activities and provides administrative support, and guidance without micromanaging individual project teams. The Core will be responsible for scheduling, organizing, hosting and/or facilitating on a regular basis the meetings that support the progress ofthe PPG. These meetings include (i)-plenary meetings (including Advisors), (ii)-electronic meetings, (iii)-thematic meetings of research groups enabled by participation of PPG teams in National and International conferences. The Core is responsible forthe administration of travel support for these meetings, including the allocation and accounting of funds. The Core is assuring compliance with all institutional, governmental and NIH-specific regulations and requirements, including timely communication with, and Progress Reporting to the NIH. All financial reporting and coordination aspects ofthe PPG that encompasses several major Institutions here and abroad are managed as well through the Core activities. Additional management objectives are to make certain that decisions about allocation (and reallocation) of resources, project expectations and progress, and accomplishing the goals of the PPG are addressed appropriately, fairly and in a well thought out and timely manner. The Core will thus continue to function to ensure the highest possible impact ofthe PPG's scientific discovery and dissemi¿¿ nation activities by (l)-providing the necessary oversight, coordination and administrative support that will ensure the optimal performance of the PPG and its Consortium activities; (2)-providing services in the computational biology and bioinformatics aspects ofthe PPG, including resource sharing, and the sharing and dissemination of data generated by this Consortium; and (3)-developing an Information Management System forthe area of research represented by the PPG, including the computer-facilitated expert annotation system TRansporter Annotation Center (TRAC), and the associated literature-mining tool Coupler. RELEVANCE (See instructions): We study a complex set on cellular machines and functions in a coordinated scientific effort to understand mechanisms essential to maintaining human health and combating disease, such as drug abuse. To bring these efforts together in an efficient and coordinated manner we use an administrative core that fosters the highest standards of scientific research, compliance with all rules and regulation, and the sharing of resources and rasults within the Consortium and the communitv at larae