REDOX BIOCHEMISTRY
REDOX BIOCHEMISTRY
批准号:
8250451
负责人:
Vadim N. Gladyshev
金额:
$19.37万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-04-01 至 2015-03-31
关键词:
AlkylationAreaBiochemistryBioinformaticsBiological AssayBiological ModelsBiologyCell Culture SystemCell ExtractsCell NucleusCellsClinicalCollectionComplementConsultationsCytosolDisulfidesEndoplasmic ReticulumEndothelial CellsEquipmentF2-IsoprostanesFluorescenceFunctional disorderGene Expression ProfileGlutathioneGlutathione DisulfideGoalsHomeostasisHuman ResourcesHydrogen PeroxideIndividualInvestigationKnowledgeLabelLeadershipLinkLungMeasurementMeasuresMetabolicMetabolismMethodsMitochondriaMitochondrial MatrixMonitorMusNADPOxidation-ReductionOxidoreductasePeroxidesProcessProteinsProteomeReagentRegulationResearchResearch PersonnelServicesSignal TransductionStructureSulfhydryl CompoundsSystemThioredoxinbasedesignenzyme activitygenetic manipulationglutathione peroxidaseimprovedinstrumentationmethionine sulfoxide reductaseoverexpressionoxidant stressratiometricresearch studyselenoproteinsensorthioredoxin reductasetool
中文摘要
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英文摘要
BACKGROUND AND SIGNIFICANCE
All four Projects in the PPG require expertise in thiol-based redox regulation and/or selenoproteins. The proposed Core C leadership has a strong track record in precisely these areas, as well as in collaborative research in general. Core C is among the few groups in the world with the necessary knowledge, expertise, instrumentation, and reagents to carry out experiments on thiol-based redox processes and selenoproteins; and has a collection of unique tools by which to do so. The Core will aid in the design of relevant experiments and their interpretation.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
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依托单位:
Systems level understanding of selenoprotein biosynthesis
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项目类别:
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依托单位:
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财政年份:2018
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依托单位:
Comparative genomics and epigenomics of aging
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