Angiotensin-(1-7) Inhibition of Hypertrophy & Fibrosis

血管紧张素-(1-7) 抑制肥大

• 批准号: 8250037
• 负责人: Ann Ann Tallant
• 金额: $ 25.83万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8250037
• 关键词: Aging; Angiotensin II; Angiotensins; Attenuated; Biochemical; Blood Pressure; Blood Vessels; Cardiac; Cardiac Myocytes; Cell Proliferation; Cells; Chronic; Collagen; Congenic Strain; Coronary artery; DUSP1 gene; Down-Regulation; Endothelin; Enzymes; Fibroblasts; Fibrosis; Funding; G-Protein-Coupled Receptors; Goals; Growth; Heart; Heart Diseases; Heart failure; Hormones; Hypertension; Hypertrophy; In Vitro; Inflammation; Inflammatory Response; Lentivirus Vector; MAPK1 gene; MAPK3 gene; Measures; Mediating; Mitogen-Activated Protein Kinases; Mitogens; Modeling; Molecular; Molecular Biology; Muscle Cells; Myocardial; Myocardial Infarction; Pathology; Peptides; Perivascular Fibrosis; Phosphoric Monoester Hydrolases; Phosphorylation Inhibition; Physiological; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthase; Prostaglandins; Protein phosphatase; Rattus; Reperfusion Injury; Role; Smooth Muscle Myocytes; Structure; Subfamily lentivirinae; Techniques; Therapeutic; Therapeutic Agents; Up-Regulation; aged; angiotensin I (1-7); base; cell growth; cyclooxygenase 2; hemodynamics; human TGFB1 protein; in vivo; indexing; interstitial; normotensive; preclinical study; pressure; prostaglandin E synthase; response; response to injury; small hairpin RNA; tissue/cell culture