Mechanisms of Meditation

冥想的机制

基本信息

批准号：
7820780
负责人：
Charles Raison
金额：
$ 55.11万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-30 至 2012-09-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7820780
关键词：
Address Adult Affect Age American Anger Anxiety Area Attention Behavior Behavioral Bite Clinical Trials Cognition Collection Compassion Computers Control Groups Data Distress Dose Education Ego Emotional Emotions Equipment Evaluation Event Funding Generations Grant Group Practice Guidelines Health Health education Hostility Hour Human Resources Immune Individual Inflammatory Inflammatory Response Intervention Intervention Studies Laboratories Language Learning Life Life Style Loneliness Measures Mediating Meditation Methodology Molecular Monitor National Center for Complementary and Alternative Medicine Nature Neurosecretory Systems Outcome Outcome Measure Parents Patient Self-Report Pattern Peripheral Persons Phase Physiological Pilot Projects Procedures Protocols documentation Psychosocial Stress Public Health Randomized Recovery Research Sampling Signal Pathway Social Environment Social support Speech Stress Techniques Testing Time Training Trier Social Stress Test United States National Institutes of Health Wages Well in self active control affiliative behavior base depression design fighting improved longitudinal design mindfulness novel post intervention psychosocial public health relevance response satisfaction secondary outcome social integration sound stressor

项目摘要

DESCRIPTION (provided by applicant): This application is submitted in response to NOT-OD-09-058 "NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications". This supplement is intended to significantly expand the scope of our NCCAM-funded R01 Project entitled "Mechanisms of Meditation" (R01AT004698-01) by adding a completely novel methodology to assess whether different meditation practices have unique effects on naturalistic, real-world speech and behavior that is relevant to emotional well-being and positive psychosocial connectivity. This competitive supplement proposes an initial, but adequately powered, study to be completed in two years that addresses two inter-related priority areas of focus for NCCAM American Recovery and Reinvestment Act (RRA) funding, including: Novel and potentially richer secondary outcome measures Collection of additional data in ongoing clinical trials that will broaden the depth and/or scope of outcome measures. In keeping with NCCAM ARRA guidelines the bulk of requested funds will support new personnel for the project and/or will increase percent effort of key personnel to provide them salary support to devote time to the project expansion. As per guidelines, funding is also being requested for the purchase of computers and small equipment specifically required to conduct the competitive supplement protocol. In this supplement we propose to use the existing randomized, longitudinal, 3-group design of the Parent R01 to examine whether meditation affects real world, naturalistic speech and behavior in ways that-based on prior studies-would be expected to enhance emotional well being and health not just of the meditation practitioner but of other people in his or her social environment. In addition, a unique feature of the proposed project is that the Parent R01 design will allow for a comparison of two different meditation practices-compassion meditation and Mindful Attention Training (MAT)-in terms of effects on objective markers of individual emotional well-being and emotional stability, as well as on speech and behavior patterns known to promote positive psychosocial connectivity. In this regard, the current proposal may provide important new data on the potential of specific meditation techniques to improve public health via improved psychosocial functioning on the part of trained practitioners. Finally, this supplement will allow us to conduct the first ever examination of whether autonomic, neuroendocrine, innate immune and behavioral responses to a standardized laboratory psychosocial stressor (Trier Social Stress Test [TSST]) are associated with naturalistic language use and real world behavior. PUBLIC HEALTH RELEVANCE: This supplement application will expand the scope of our NCCAM-funded project entitled "Mechanisms of Meditation" by adding a novel methodology to assess whether different meditation practices have unique effects on naturalistic, real-world speech and behavior that is relevant to emotional well-being and positive psychosocial connectivity. Funds requested will support new personnel for the project and will increase percent effort of key personnel to provide them salary support to devote time to the project expansion. This supplement proposes an initial study that addresses two inter-related priority areas of focus for the American Recovery and Reinvestment Act (ARRA), including the enrichment of the original proposal with enhanced secondary outcome measures, and collection of additional data in ongoing clinical trials that will broaden the depth and/or scope of outcome measures.