Vanderbilt Meharry Center for AIDS Research
Vanderbilt Meharry Center for AIDS Research
批准号:
8304644
负责人:
Spyros A Kalams
金额:
$64.47万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-05-15 至 2014-08-31
中文摘要
Vanderbilt-Meharry CFAR(CFAR)将在田纳西州纳什维尔的这两个互补机构(范德比尔特大学医学中心和Meharry医学院)之间现有的强有力的互动基础上,为艾滋病研究开发更好的基础设施支持,并加强多学科的合作环境。将在与艾滋病毒流行病学/预防、发病机制和治疗有关的所有领域促进创新研究。目前转化和发病机制研究的优势将得到加强,包括建设全面研究与艾滋病毒疾病相关的种族差异的能力。
Vanderbilt-Meharry CFAR将通过4个核心发挥作用:发育,临床发现,免疫发病机制和病毒学。这些核心反映了在病毒发病机制,免疫生物学和抗逆转录病毒药物基因组学的转化研究的优势;一个全面的临床数据库/标本档案;在非艾滋病毒相关领域以及艾滋病毒疾病的独特成果研究合作实力;几个国家临床试验网络的持续生产单位CFAR也将支持少数民族科学家的发展,加强对社区的宣传和对生物医学受训人员/科学家的艾滋病研究教育,并加强国际艾滋病毒研究。科学计划将鼓励新的合作项目。Vanderbilt-Meharry CFAR提供的协调、合作和种子资源将大大加快这些机构艾滋病研究的扩展。
英文摘要
The Vanderbilt-Meharry CFAR (CFAR) will build on existing strong interactions between these two complementary institutions (Vanderbilt University Medical Center and Meharry Medical College) in Nashville, Tennessee to develop improved infrastructure support, and to enhance the multidisciplinary, collaborative environment, for AIDS research. Innovative research will be promoted in all areas relevant to HIV epidemiology/prevention, pathogenesis, and treatment. Current strengths in translational and pathogenesis research will be bolstered, including building capacity to comprehensively study racial disparities relevant to HIV disease.
The Vanderbilt-Meharry CFAR will function through 4 Cores: Developmental, Clinical Discovery, Immunopathogenesis, and Virology. These Cores reflect the strengths in translational research in virus pathogenesis, immunobiology, and antiretroviral pharmacogenomics; a comprehensive clinical database/specimen archive; unique outcomes research collaborative strength in non-HIV-related areas as well as in HIV disease; and consistently-productive units of several national clinical trials networks CFAR will also support development of minority scientists, improve outreach to the community and education for biomedical trainees/scientists about AIDS research, and enhance international HIV research. Scientific programs will encourage new collaborative projects. The coordination, collaboration, and seeding resources provided by the Vanderbilt-Meharry CFAR will greatly accelerate expansion of AIDS research at these institutions.
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DOI:
10.1016/j.tube.2007.05.008
发表时间:
2007-08
期刊:
Tuberculosis
影响因子:
3.2
作者:
[S. Vermund;N. Yamamoto]
通讯作者:
S. Vermund;N. Yamamoto
DOI:
10.1086/592693
发表时间:
2008-11-15
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
作者:
[Rebeiro PF, Kheshti A, Bebawy SS, Stinnette SE, Erdem H, Tang YW, Sterling TR, Raffanti SP, D'Aquila RT]
通讯作者:
D'Aquila RT
Postpartum discontinuation of antiretroviral therapy and risk of maternal AIDS-defining events, non-AIDS-defining events, and mortality among a cohort of HIV-1-infected women in the United States.
美国一群 HIV-1 感染妇女产后停止抗逆转录病毒治疗以及孕产妇艾滋病定义事件、非艾滋病定义事件和死亡率的风险。
DOI:
10.1089/apc.2009.0283
发表时间:
2010
期刊:
AIDS patient care and STDs
影响因子:
4.9
作者:
[Melekhin,VladaV, Shepherd,BryanE, Jenkins,CathyA, Stinnette,SamuelE, Rebeiro,PeterF, Bebawy,SallyS, Rasbach,DanielA, Hulgan,Todd, Sterling,TimothyR]
通讯作者:
Sterling,TimothyR
DOI:
10.1186/1471-2334-14-508
发表时间:
2014-09-18
期刊:
BMC infectious diseases
影响因子:
3.7
作者:
[Qian HZ, Mitchell VJ, Bebawy S, Cassell H, Perez G, McGowan CC, Sterling TR, Vermund SH, D'Aquila R, Hulgan T]
通讯作者:
Hulgan T
DOI:
10.1371/journal.pone.0133509
发表时间:
2015
期刊:
PloS one
影响因子:
3.7
作者:
[Chukwuma VU, Hicar MD, Chen X, Nicholas KJ, Joyner A, Kalams SA, Landucci G, Forthal DN, Spearman PW, Crowe JE Jr]
通讯作者:
Crowe JE Jr
共 22 条
Single cell molecular analysis of influenza vaccine responses in elderly individuals
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批准号:10574601
-
项目类别:
-
资助金额:$47.49万
-
财政年份:2019
-
负责人:Spyros A Kalams
-
依托单位:
Single cell molecular analysis of influenza vaccine responses in elderly individuals
-
批准号:10887735
-
项目类别:
-
资助金额:$43.65万
-
财政年份:2019
-
负责人:Spyros A Kalams
-
依托单位:
Single cell molecular analysis of influenza vaccine responses in elderly individuals
-
批准号:10383653
-
项目类别:
-
资助金额:$47.39万
-
财政年份:2019
-
负责人:Spyros A Kalams
-
依托单位:
Molecular analysis of the adaptive immune response to tuberculosis
-
批准号:9204642
-
项目类别:
-
资助金额:$23.41万
-
财政年份:2016
-
负责人:Spyros A Kalams
-
依托单位:
Molecular analysis of the adaptive immune response to tuberculosis
-
批准号:9346014
-
项目类别:
-
资助金额:$19.75万
-
财政年份:2016
-
负责人:Spyros A Kalams
-
依托单位:
Laboratory Sciences Core (Core D)
-
批准号:10404938
-
项目类别:
-
资助金额:$33.29万
-
财政年份:2015
-
负责人:Spyros A Kalams
-
依托单位:
Laboratory Sciences Core (Core D)
-
批准号:10617300
-
项目类别:
-
资助金额:$23.46万
-
财政年份:2015
-
负责人:Spyros A Kalams
-
依托单位:
Laboratory Sciences Core (Core D)
-
批准号:10153673
-
项目类别:
-
资助金额:$50.99万
-
财政年份:2015
-
负责人:Spyros A Kalams
-
依托单位:
Pro-Apoptotic BCG as an HCV vaccine vector
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批准号:7386674
-
项目类别:
-
资助金额:$24.56万
-
财政年份:2009
-
负责人:Spyros A Kalams
-
依托单位:
Pro-Apoptotic BCG as an HCV vaccine vector
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批准号:7936880
-
项目类别:
-
资助金额:$19.33万
-
财政年份:2009
-
负责人:Spyros A Kalams
-
依托单位:
Characterization of T & B cell responses correlated with broad neutralizing Abs
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批准号:7663383
-
项目类别:
-
资助金额:$53.16万
-
财政年份:2009
-
负责人:Spyros A Kalams
-
依托单位:
Characterization of T & B cell responses correlated with broad neutralizing Abs
-
批准号:8913416
-
项目类别:
-
资助金额:$36.95万
-
财政年份:2009
-
负责人:Spyros A Kalams
-
依托单位:
Molecular Analysis of HCV-specific T Cell Responses
-
批准号:7014196
-
项目类别:
-
资助金额:$23.93万
-
财政年份:2005
-
负责人:Spyros A Kalams
-
依托单位:
HIV IMMUNOPATHOGENESIS
-
批准号:8330528
-
项目类别:
-
资助金额:$14.23万
-
财政年份:2003
-
负责人:Spyros A Kalams
-
依托单位:
Molecular analysis of HCV T cell responses
-
批准号:6652717
-
项目类别:
-
资助金额:$43.42万
-
财政年份:2002
-
负责人:Spyros A Kalams
-
依托单位:
Molecular analysis of HCV T cell responses
-
批准号:6493586
-
项目类别:
-
资助金额:$43.42万
-
财政年份:2001
-
负责人:Spyros A Kalams
-
依托单位:
Molecular analysis of HCV T cell responses
-
批准号:6349586
-
项目类别:
-
资助金额:$43.42万
-
财政年份:2000
-
负责人:Spyros A Kalams
-
依托单位:
TCR Genes and HIV-Specific Cytotoxic T-lymphocytes
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批准号:6496461
-
项目类别:
-
资助金额:$33.79万
-
财政年份:1997
-
负责人:Spyros A Kalams
-
依托单位:
TCR GENE USAGE AND QUANTITATION OF HIV SPECIFIC CTL
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批准号:2330455
-
项目类别:
-
资助金额:$20.9万
-
财政年份:1997
-
负责人:Spyros A Kalams
-
依托单位:
TCR GENE USAGE AND QUANTITATION OF HIV SPECIFIC CTL
-
批准号:2672781
-
项目类别:
-
资助金额:$20.03万
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财政年份:1997
-
负责人:Spyros A Kalams
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依托单位:
海外基金