Administration and Mgmt (California)

行政和管理（加利福尼亚州）

• 批准号: 8332830
• 负责人: HUGH ROSEN
• 金额: $ 219.47万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8332830
• 关键词: Area; Attention; Biological Assay; Budgets; California; Chemicals; Chemistry; Consultations; Goals; Head; Informatics; Lead; Metric; Monitor; Resolution; Screening procedure; Therapeutic; Time; United States National Institutes of Health; assay development; base; experience; meetings

D8.2 Administration and Management: The TSRI Center will be administered by the PI in consultation with the Center Screening Committee. The functional cores (Assay Implementation, uHTS Implementation, Informatics, PK, Chemistry and QA) will meet on a monthly basis to set goals and metrics towards those interim goals, as well as monitor progress towards the global Specific Aims with their timed milestones. Variances of > 1 Quarter from the planned global milestones will be flagged by the PI and brought to the attention of the CSC. Remedial steps will be taken in real time to solve the specific problems. Should the PI, in consultation with the CSC, identify variances that, after remedial steps have been taken, still impact on scope or timeliness of deliverables, the PI will draw this to the attention of NIH staff where appropriate and seek guidance. In addition to the successful implementation ahead of time and on budget of the MLSCN Center and chairing the MLSCN Steering Group, the PI had significant therapeutic area head level industrial experience at Merck. It is well within his capabilities to define key Center problems and lead them to resolution at the appropriate level within the Center or the NIH Project Team. Integration of Assay Development, Adaptation and uHTS implementation is managed by the monthly meeting of the Screening Coordination Committee (SCC).

D8.2 行政和管理：TSRI 中心将由 PI 与 中心筛选委员会。功能核心（检测实施、uHTS 实施、 信息学、PK、化学和质量保证）将每月举行一次会议，以确定这些目标和指标 中期目标，并通过其定时里程碑监测全球具体目标的进展情况。 与计划的全球里程碑相比超过 1 个季度的差异将由 PI 标记并提交给 引起CSC的关注。针对具体问题，将实时采取补救措施。如果PI，在 与 CSC 协商，确定在采取补救措施后仍然影响范围的差异 或交付成果的及时性，PI 将在适当的情况下提请 NIH 工作人员注意，并寻求 指导。除了在预算范围内提前成功实施 MLSCN 中心外， 作为 MLSCN 指导小组的主席，PI 在以下机构拥有丰富的治疗领域领导级行业经验： 默克。他完全有能力确定中心的关键问题并引导它们在中心得到解决。 中心或 NIH 项目团队内的适当级别。检测开发、适应和检测的整合 uHTS 的实施由筛选协调委员会 (SCC) 的每月会议进行管理。