Methionine Adenosyltransferase as a Therapeutic Target for Liver Fibrosis
Methionine Adenosyltransferase as a Therapeutic Target for Liver Fibrosis
批准号:
8318437
负责人:
Komal Ramani
金额:
$23.83万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-06-07 至 2014-05-31
关键词:
AddressAlcohol consumptionAnabolismAnimal ModelAwardBiliaryBindingBiochemicalBiologicalBlood PlateletsCatalytic DomainCell LineChronicDevelopmentDoseElementsEnzymesEventExtrahepaticFibrosisGene ExpressionGene SilencingGenesGrowth FactorHepatic Stellate CellHepatitisHepatocyte Growth FactorHumanIn VitroInjuryInstructionIsoenzymesLeptinLigationLiverLiver CirrhosisLiver FibrosisLiver diseasesMalignant - descriptorMalignant neoplasm of liverMammalian CellMethionineMethylationModelingMolecularMolecular Biology TechniquesObstructionOutcomePPAR gammaPPAR-betaPathway interactionsPeroxisome Proliferator-Activated ReceptorsPhasePlatelet-Derived Growth FactorPlayPolyaminesPrimary carcinoma of the liver cellsProcessRattusResearch PersonnelRoleS-AdenosylmethionineSignal TransductionTransferaseTransferase GeneWorkbile ductcancer cellcell growthin vivoinhibitor/antagonistinsightinterestliver cell proliferationmethionine adenosyltransferasenovelnovel therapeutic interventionpromoterresearch studyresponsetherapeutic developmenttherapeutic targettreatment strategy
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会议论文
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依托单位:
海外基金