Liver fibrosis and ethanol: role of the transcription factor, Egr-1

肝纤维化和乙醇：转录因子 Egr-1 的作用

• 批准号: 8263799
• 负责人: MICHELE T PRITCHARD
• 金额: $ 24.9万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-08 至 2014-07-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8263799
• 关键词: Acute; Acute Hepatitis; Address; Antioxidants; Attenuated; Award; Biological Models; CCL2 gene; COL1A2 gene; CXCL2 gene; CYP2E1 gene; Carbon Tetrachloride; Cell Culture Techniques; Cell Cycle; Cell Cycle Progression; Cell physiology; Cells; Characteristics; Chronic; Cirrhosis; Collagen; Collagen Diseases; Data; Development; Disease; Dose; Early Gene Transcriptions; Endothelial Cells; Endotoxemia; Enzymes; Ethanol; Extracellular Matrix; Fatty Liver; Fibrosis; Gene Expression; Generations; Genes; Growth; Health; Hepatic; Hepatic Stellate Cell; Hepatocyte; Immediate-Early Genes; Inflammation; Inflammatory; Injury; Injury to Liver; Instruction; Intercellular adhesion molecule 1; Ischemia; Kupffer Cells; Lead; Literature; Liver; Liver Fibrosis; Liver diseases; Maintenance; Matrix Metalloproteinases; Mediating; Mediator of activation protein; Modeling; Molecular; Mus; Outcome; Patients; Phenotype; Platelet-Derived Growth Factor; Play; Process; Production; Publishing; Recovery; Reperfusion Therapy; Resolution; Role; Staging; Steatohepatitis; TIMP1 gene; Therapeutic; Toxin; United States; Work; Wound Healing; alcohol exposure; base; cell type; chronic alcohol ingestion; design; feeding; fibrogenesis; hepatotoxin; improved; injury and repair; liver cell proliferation; liver transplantation; novel; novel therapeutics; oval cell; response; transcription factor