University of New Mexico Clinical and Translational Science Center

新墨西哥大学临床和转化科学中心

• 批准号: 8295016
• 负责人: RICHARD S LARSON
• 金额: $ 30.37万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8295016
• 关键词: Achievement; Address; Affect; Area; Award; Basic Science; Biomedical Research; Biotechnology; Boston; Center for Translational Science Activities; Centers of Research Excellence; Child health care; Clinical; Clinical Research; Clinical Sciences; Collaborations; Commit; Communities; Community Healthcare; Community Physician; Country; Coupled; Data Security; Databases; Development; Discipline; Discipline of Nursing; Disease; District of Columbia; Education; Effectiveness; Environment; Equilibrium; Evaluation; Extramural Activities; Faculty; Fostering; Funding; Generations; Geographic Locations; Goals; Grant; Growth; Health; Health Sciences; Health Services Research; Healthcare; Hispanic Americans; Hispanics; Home environment; Human; Immersion Investigative Technique; Incentives; Incubators; Individual; Industry; Information Technology; Institution; Institutional Review Boards; Investigation; Investments; Knowledge; Laboratories; Leadership; Letters; Link; Marshal; Master of Science; Master' s Degree; Medical; Medical Research; Mentors; Methodology; Methods; Minority; Mission; Modeling; Montana; National Children' s Study; Native Americans; Nevada; New Mexico; Outcome; Outpatients; Participant; Patient Care; Pediatrics; Pharmacy facility; Phase; Pilot Projects; Policy Maker; Population; Population Heterogeneity; Poverty; Process; Recording of previous events; Recruitment Activity; Reporting; Research; Research Activity; Research Infrastructure; Research Personnel; Research Priority; Research Support; Resources; Rural; SECTM1 gene; Scholarship; Schools; Science; Scientist; Senior Scientist; Speed; Strategic Planning; System; Techniques; Technology; Testing; Time; Training; Training Programs; Training and Education; Translating; Translational Research; Translations; United States; United States National Institutes of Health; Universities; University Hospitals; Vision; Work; Wyoming; authority; base; biomedical informatics; career development; clinical data warehouse; clinical practice; collaboratory; college; design; expectation; experience; health disparity; improved; industry partner; innovation; knowledge base; medical schools; member; multidisciplinary; novel; operation; prevent; programs; research and development; socioeconomics; translational study

This proposal for a Clinical and Translational Science Center at the University of New Mexico Health Sciences Center (HSC) will catalyze the emergence of a transformative, novel, and integrated academic home for clinical and translational science at a flagship institution that serves the entire state of New Mexico and the Southwestern region of the U.S. This center will have the infrastructure and consolidated resources to: 1) synergize multi- and interdisciplinary clinical and translational research and researchers to catalyze the application of new knowledge and techniques to clinical practice at the front lines of patient care; 2) recruit, train, and advance well-trained Interdisciplinary investigators and research teams with strength In cultural sensitivity, health disparity, and biotechnology; 3) create an incubator for innovative research and information technologies; and 4) expand existing partnerships between UNM Health Sciences Center (HSC) researchers, practicing clinicians, and communities to speed the development of research. Our vision of the CTSC links and focuses the efforts of our basic, clinical, and translational investigators, community clinicians, clinical practices, health care and research collaborators, and industry partners. Since New Mexico has a high proportion of ethnically diverse (i.e., Hispanic and Native American), rural, medically disenfranchised, and health-disparate populations, a CTSC in New Mexico can uniquely address these problems. The UNM CTSC will draw upon outstanding Institutional commitment (at least $57,802,262 ) to achieve its goals. The UNM CTSC possesses authority over the recruiting, hiring, protected time, expectations, promotion and tenure, and evaluation of its faculty members. Evidence of the commitment and effectiveness of the UNM CTSC In these pursuits are apparent from the following achievements made during the planning process: (1) reorganization of the UNM HSC research mission under a new Vice President for Translational Research with authority over research education, compliance and research functions, (2) establishment of an institutionally-funded K12-llke program, and recruitment of 5 junior faculty, (3) development of Innovative new research education programs, (4) operation of a functionally expanded Participant and Clinical Interactive Resources component that is serving the needs of several community-based studies, Including the landmark, new National Children's Study, (5) the redesign of our institutional approach to Biomedical Informatics and development of a regional clinical data warehouse that will be available to Investigators using a $5.8 M Investment, and (6) construction and renovation of new buildings for the CTSC. Additionally, UNM's commitment Includes $14.5 M In new institutional funds committed to CTSC programs, and $8.5 M in matching funds to construct new space to create a physical home for the CTSC. Funding of this proposal will assure sustainability and growth of these transformations that Is critically needed to support clinical and translational research at UNM.

新墨西哥大学健康科学中心 (HSC) 临床和转化科学中心的这一提议将促进在服务于整个新墨西哥州和美国西南部地区的旗舰机构中建立一个变革性的、新颖的、综合性的临床和转化科学学术中心。该中心将拥有基础设施和整合的资源，以：1) 协同多学科和跨学科的临床和转化科学中心。 转化研究和研究人员促进新知识和技术在患者护理第一线的临床实践中的应用； 2）招募、培训和培养训练有素的跨学科研究人员和研究团队，在文化敏感性、健康差异和生物技术方面具有优势； 3）创建创新研究和信息技术孵化器； 4) 扩大新墨西哥大学健康科学中心 (HSC) 研究人员、执业临床医生和社区之间的现有合作伙伴关系，以加快研究发展。我们的 CTSC 愿景将我们的基础、临床和转化研究人员、社区临床医生、临床实践、医疗保健和研究合作者以及行业合作伙伴的努力联系起来并集中起来。由于新墨西哥州拥有大量不同种族（即西班牙裔和美洲原住民）、农村人口、被剥夺医疗权利和健康状况差异的人口，新墨西哥州的 CTSC 可以独特地解决这些问题。 UNM CTSC 将利用未履行的机构承诺（至少 57,802,262 美元）来实现其目标。 UNM CTSC 拥有对其教职人员的招聘、雇用、保护时间、期望、晋升和任期以及评估的权力。 UNM CTSC 的承诺和有效性的证据 在这些追求中，规划过程中取得的以下成就显而易见：(1) 在新的转化研究副总裁的领导下重组了 UNM HSC 研究任务，负责研究教育、合规和研究职能，(2) 建立一个由机构资助的 K12-llke 项目，并招聘 5 名初级教师，(3) 开发创新的新研究教育项目， (4) 运营功能扩展的参与者和临床互动资源组件，满足多项基于社区的研究的需求，包括具有里程碑意义的新的国家儿童研究，(5) 重新设计我们的生物医学信息学机构方法，并开发一个区域临床数据仓库，该数据仓库将供研究人员使用 580 万美元的投资使用，以及 (6) 为 CTSC 建造和翻新新建筑。此外，UNM 的承诺包括用于 CTSC 项目的 1,450 万美元新机构基金，以及用于建造新空间为 CTSC 创建实体家园的 850 万美元配套资金。该提案的资助将确保这些转型的可持续性和增长，这是支持新墨西哥州临床和转化研究所迫切需要的。

项目成果

Prevention of postoperative osteopenia using IV pamidronate: a pilot study.

使用静脉注射帕米膦酸盐预防术后骨质减少：一项试点研究。

• DOI: 10.1097/bpo.0b013e3182a11d0c
• 发表时间: 2013
• 期刊: Journal of pediatric orthopedics
• 作者: Hobby,BryonD;Dominguez-Bartmess,Samuel;Szalay,ElizabethA
• 通讯作者: Szalay,ElizabethA

Is the protocol for induction of labor in singletons applicable to twin gestations?

单胎引产方案是否适用于双胎妊娠？

• 发表时间: 2013
• 期刊: The Journal of reproductive medicine
• 作者: Wolfe,MichaelD;delaTorre,Lesley;Moore,LisaE;Myers,Orrin;Rayburn,WilliamF
• 通讯作者: Rayburn,WilliamF

Is the masked continuous glucose monitoring system clinically useful for predicting hemoglobin A1C in type 1 diabetes?

隐蔽连续血糖监测系统在临床上对预测 1 型糖尿病患者的血红蛋白 A1C 有用吗？

• DOI: 10.1089/dia.2013.0297
• 发表时间: 2014
• 期刊: Diabetes technology & therapeutics
• 影响因子: 5.4
• 作者: Duran-Valdez,Elizabeth;Burge,MarkR;Broderick,Paula;Shey,Lynda;Valentine,Virginia;Schrader,Ronald;Schade,DavidS
• 通讯作者: Schade,DavidS

A model for conditional male trimorphisms.

条件雄性三态性的模型。

• DOI: 10.1016/j.jtbi.2017.02.006
• 发表时间: 2017
• 期刊: Journal of theoretical biology
• 影响因子: 2
• 作者: MarkRowland,J;Qualls,CliffordR;Buzatto,BrunoA
• 通讯作者: Buzatto,BrunoA

DOES SHORT-TERM VITAMIN C REDUCE CARDIOVASCULAR RISK IN TYPE 2 DIABETES?

• DOI: 10.4158/ep12431.or
• 发表时间: 2013-09-01
• 期刊: ENDOCRINE PRACTICE
• 影响因子: 4.2
• 作者: Gutierrez, Absalon D.;Duran-Valdez, Elizabeth;Schade, David S.
• 通讯作者: Schade, David S.