Posttranslational Modification of Deubiquitinating Enzymes in Neurodegeneration
Posttranslational Modification of Deubiquitinating Enzymes in Neurodegeneration
批准号:
8203082
负责人:
Sokol Todi
金额:
$24.9万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-30 至 2013-11-30
关键词:
AddressAffectAlzheimer&aposs DiseaseAmericanAmyloid beta-Protein PrecursorAnimal ModelAnimalsAutophagocytosisAwardBehavioralBindingBinding SitesBiological AssayBrainCatalogingCatalogsCatalytic DomainCell Culture TechniquesCell LineCell NucleusCell modelCell physiologyCellsCleaved cellComputer SimulationDataDatabasesDeubiquitinating EnzymeDeubiquitinationDiseaseDisease modelDrosophila genusDrosophila melanogasterEyeFutureGeneticGoalsHeat Stress DisordersHomeostasisHumanIn VitroInstructionLigaseLinkLysineMJD1 proteinMachado-Joseph DiseaseMaintenanceMammalian CellManuscriptsModelingMolecularMolecular WeightMusNerve DegenerationNervous system structureNeurodegenerative DisordersNeurogliaNeuronsParkinson DiseasePathogenesisPathway interactionsPhasePhysiologicalPlayPositioning AttributePost-Translational Protein ProcessingProcessProteasome InhibitionProteinsPublicationsPublishingQuality ControlRNA InterferenceRecombinant ProteinsRegulationReportingResearchResourcesRoleSiteStressTertiary Protein StructureTestingUbiquitinUbiquitinationUp-RegulationUpdateWorkage relatedaging brainalpha synucleinataxin-1basecell typeflyfollow-upin vitro Assayinsightinterestlactacystinmembermouse modelmulticatalytic endopeptidase complexmutantneurotoxicpolyglutamineprotein degradationprotein functionprotein misfoldingresponsestressorsynucleintau Proteinstau mutationubiquitin-protein ligase
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会议论文
Exercise-dependent mechanisms of protection in polyglutamine degeneration
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批准号:10188094
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资助金额:$42.35万
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Unique ubiquitin processes in misfolded protein diseases of the nervous system
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批准号:10284055
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依托单位:
Protection against Alzheimer's Disease proteins by novel ubiquitin processes
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批准号:10283294
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项目类别:
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资助金额:$23.65万
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依托单位:
Molecular Mechanisms of Neuroprotection in Polyglutamine-Dependent Degeneration
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批准号:10115135
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财政年份:2014
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Molecular Mechanisms of Neuroprotection in Polyglutamine-Dependent Degeneration
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批准号:9811467
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资助金额:$31.55万
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财政年份:2014
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Molecular Mechanisms of Neuroprotection in Polyglutamine-Dependent Degeneration
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批准号:10369021
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项目类别:
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资助金额:$37.95万
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财政年份:2014
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Molecular Mechanisms of Neuroprotection in Polyglutamine-Dependent Degeneration
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批准号:9018062
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资助金额:$33.25万
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财政年份:2014
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负责人:Sokol Todi
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依托单位:
Molecular Mechanisms of Neuroprotection in Polyglutamine-Dependent Degeneration
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批准号:8667610
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项目类别:
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资助金额:$33.25万
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财政年份:2014
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负责人:Sokol Todi
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依托单位:
Molecular Mechanisms of Neuroprotection in Polyglutamine-Dependent Degeneration
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批准号:9234079
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项目类别:
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资助金额:$33.25万
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财政年份:2014
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负责人:Sokol Todi
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依托单位:
Posttranslational Modification of Deubiquitinating Enzymes in Neurodegeneration
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批准号:8394928
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项目类别:
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资助金额:$23.0万
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财政年份:2009
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负责人:Sokol Todi
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依托单位:
Posttranslational Modification of Deubiquitinating Enzymes in Neurodegeneration
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批准号:7738174
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项目类别:
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资助金额:$8.56万
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财政年份:2009
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负责人:Sokol Todi
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依托单位:
Posttranslational Modification of Deubiquitinating Enzymes in Neurodegeneration
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批准号:8206841
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项目类别:
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资助金额:$24.52万
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财政年份:2009
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负责人:Sokol Todi
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依托单位:
海外基金