Arkansas Center for Clinical and Translational Research

阿肯色州临床和转化研究中心

• 批准号: 8262115
• 负责人: Curtis L Lowery
• 金额: $ 3.62万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-14 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8262115
• 关键词: Academic Medical Centers; Address; Ambulatory Care Facilities; Area; Area Health Education Centers; Arkansas; Award; Basic Science; Behavioral Research; Biological; Biometry; Budgets; Caring; Caucasians; Caucasoid Race; Cessation of life; Child; Childhood; Clinic; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Practice; Complex; Data; Death Rate; Development; Diabetes Mellitus; Discipline of Nursing; Disease; Education; Effectiveness; Epidemiology; Ethics; Family Practice; Fostering; Foundations; Funding; Future; Geriatrics; Goals; Grant Review; Health; Health Policy; Health Sciences; Health Services; Health Services Accessibility; Health Services Research; Health Status; Healthcare; Heart Diseases; Home environment; Incidence; Industry; Informatics; Institution; Journals; Knowledge; Laboratories; Lead; Leadership; Left; Licensing; Life Style; Location; Maps; Medical; Medicine; Methodology; Minority Groups; Modeling; Obesity; Paper; Participant; Patient Care; Patients; Pediatrics; Pharmacy facility; Physicians; Pilot Projects; Policy Maker; Population; Population Research; Positioning Attribute; Poverty; Problem Solving; Process; Public Health; Published Comment; Publishing; Race; Recruitment Activity; Research; Research Personnel; Resource Informatics; Resources; Role; Rural; Rural Community; Rural Population; Schools; Science; Scientist; Series; Smoking; Societies; Specialist; Stroke; Structure; System; Techniques; Technology; Telemedicine; Time; Training; Training and Education; Translating; Translational Research; United States National Institutes of Health; Universities; Vision; base; bench to bedside; clinical care; clinical practice; college; demographics; design; ethnic minority population; experience; forging; health disparity; improved; indexing; innovation; medical schools; new technology; next generation; novel; outreach; patient population; programs; research and development; skills

The University of Arkansas for Medical Sciences (UAMS) is undertaking a series of initiatives aimed at synergizing existing clinical and translational research programs, and revamping the institutional research endeavor. The Arkansas Center for Clinical and Translational Research (CCTR) has been formed which unites all UAMS Colleges and its Graduate School behind the translational research endeavor. Our overarching goal is to establish an integrative CCTR that transforms the pace, effectiveness, and quality of translational research at UAMS, resulting in better health for all Arkansans. The 4 overall goals are as follows: Specific Aim 1: Educate the next generation of physicians and scientists in collaborative translational science; Specific Aim 2: Develop partnerships with Arkansas's communities to assure that our research addresses their concerns and needs, and that they benefit from our findings; Specific Aim 3: Champion innovation and collaboration in research and discovery to bring new technologies to Arkansans; Specific Aim 4: Provide administrative structure that facilitates translational research through promoting productive interactions among basic science, clinical, health services, and health policy researchers. These goals are supported by intensive component programs (Governance, Regulatory Support, Participant and Clinical Interaction Resources, Informatics, Design/Biostatistics, Ethics, Education, Novel methodologies/Pilot studies, Translational Technologies, Community Engagement) plus 3 additional program components in which we are particularly strong, and which will serve well the greater Arkansas community: These are Health Services Research, Behavioral Research, and Epidemiology. Arkansas has an outstanding telemedicine program to support our community-based research efforts. UAMS is developing a new Division of Informatics. Thus, the Arkansas CCTR will bring considerable added value to Arkansas, and represent a model program for research that extends nationally to rural communities. The CCTR will foster the formation of a cross-disciplinary, multi-faceted interface among the laboratory bench, patient bedside, and wider community through an interactive network of scientists. It will also facilitate training of future clinical and translational investigators across the health sciences and forge strategic collaborations among researchers, community clinicians, clinical research networks, professional societies, industry, and policy makers to facilitate the development of innovative research, increase the responsiveness and efficiency of translational research, and catalyze the application of new knowledge and techniques to clinical practice at the front lines of patient care.

阿肯色大学医学科学学院（UAMS）正在开展一系列旨在协同现有临床和转化研究项目的倡议，并改进机构研究工作。阿肯色临床与转化研究中心（CCTR）成立，将阿肯色大学所有学院及其研究生院联合起来，共同致力于转化研究。我们的首要目标是建立一个综合的CCTR，以改变UAMS转化研究的速度，有效性和质量，从而为所有阿肯色州人带来更好的健康。具体目标1：培养下一代合作转化科学的医生和科学家；具体目标2：与阿肯色州社区建立伙伴关系，以确保我们的研究解决了他们的担忧和需求，并使他们从我们的研究结果中受益；具体目标3：支持研究和发现方面的创新与合作，为阿肯色州带来新技术；具体目标4：通过促进基础科学、临床、卫生服务和卫生政策研究人员之间富有成效的互动，提供有利于转化研究的行政结构。这些目标由密集的组成项目（治理、监管支持、参与者和临床互动资源、信息学、设计/生物统计学、伦理学、教育、新方法/试点研究、转化技术、社区参与）以及我们特别强大的3个额外的项目组成部分支持，这些项目组成部分将很好地服务于阿肯色州的大社区：卫生服务研究、行为研究和流行病学。阿肯色州有一个出色的远程医疗项目来支持我们以社区为基础的研究工作。UAMS正在发展一个新的信息学部门。因此，阿肯色州CCTR将为阿肯色州带来可观的附加值，并代表了一个将研究扩展到全国农村社区的示范项目。

项目成果

Multi-tiered analysis of brain injury in neonates with congenital heart disease.

• DOI: 10.1007/s00246-013-0712-6
• 发表时间: 2013
• 期刊: PEDIATRIC CARDIOLOGY
• 影响因子: 1.6
• 作者: Mulkey, Sarah B.;Swearingen, Christopher J.;Melguizo, Maria S.;Schmitz, Michael L.;Ou, Xiawei;Ramakrishnaiah, Raghu H.;Glasier, Charles M.;Schaefer, G. Bradley;Bhutta, Adnan T.
• 通讯作者: Bhutta, Adnan T.

Relationship between sleep duration and quality and glycated hemoglobin, body mass index, and self-reported health in Marshallese adults.

• DOI: 10.1016/j.sleh.2021.01.007
• 发表时间: 2021-06
• 期刊: SLEEP HEALTH
• 影响因子: 4.1
• 作者: McElfish, Pearl A.;Andersen, Jennifer A.;Felix, Holly C.;Purvis, Rachel S.;Rowland, Brett;Scott, Aaron J.;Chatrathi, Meena;Long, Christopher R.
• 通讯作者: Long, Christopher R.

Towards Large-scale Twitter Mining for Drug-related Adverse Events.

• DOI: 10.1145/2389707.2389713
• 发表时间: 2012-10-29
• 期刊: SHB'12 : proceedings of the 2012 ACM International Workshop on Smart Health and Wellbeing : October 29, 2012, Maui, Hawaii, USA. International Workshop on Smart Health and Wellbeing (2012 : Maui, Hawaii)
• 作者: Bian J;Topaloglu U;Yu F
• 通讯作者: Yu F

Subclinical doxorubicin-induced cardiotoxicity update: role of neutrophils and endothelium.

• 发表时间: 2021
• 期刊: American journal of cancer research
• 影响因子: 5.3
• 作者: V. Todorova;Jeanne Y Wei;I. Makhoul

Low bone turnover and low bone density in a cohort of adults with Down syndrome.

• DOI: 10.1007/s00198-012-2109-4
• 发表时间: 2013-04
• 期刊: OSTEOPOROSIS INTERNATIONAL
• 影响因子: 4
• 作者: McKelvey, K. D.;Fowler, T. W.;Akel, N. S.;Kelsay, J. A.;Gaddy, D.;Wenger, G. R.;Suva, L. J.
• 通讯作者: Suva, L. J.