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Research Animal Support

研究动物支持

基本信息

批准号：
8310852
负责人：
Peggy Taylor Tinkey
金额：
$ 123.48万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/8310852
关键词：
Accreditation Administrator Animal Experimentation Animal Welfare Animals Award Basic Cancer Research Beds Breeding Businesses Cancer Center Cancer Center Support Grant Capillary Electrophoresis Caring Chemistry Clinical Computers Congenic Mice Consultations Contracts Custom Development Doctor of Philosophy Doctor of Veterinary Medicine Equipment Faculty Fees Fishes Funding Future Genetic Genetic Services Genetically Engineered Mouse Genotype Grant Hamsters Health Hematology House mice Housing Human Resources IACUC Image Institution International Laboratory Animal Production and Facilities Laboratory Animals Laboratory Personnel Medical History Microsatellite Repeats Monitor Mouse Strains Mus Mutant Strains Mice Online Systems Operations Research Operative Surgical Procedures Pathology Patient Monitoring System Peer Review Population Preclinical Drug Development Procedures Production Radiation therapy Rattus Research Research Personnel Research Support Resource Sharing Rodent Science Services Single Nucleotide Polymorphism Site System Toxicology Transportation United States Department of Agriculture University of Texas M D Anderson Cancer Center Veterinarians animal care animal facility animal resource anticancer research carcinogenesis computerized genetic linkage analysis genetic pedigree genome wide association study laboratory facility operation pre-clinical programs quality assurance wasting

项目摘要

The Research Animal Support Facility (RASF) has been a shared resource since the original CCSG was awarded in 1975 and exists to support ongoing clinical and basic cancer research involving laboratory animals at MDACC. The RASF has components located in Houston at MDACC (2 campuses), and in Smithville in the Department of Carcinogenesis. All animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care International, have Animal Welfare Assurance approval (A3343-01), and are registered as research animal facilities with the United States Department of Agriculture (USDA) (74-R-065). The Research Animal Support Facility Houston (RASFH) is directed by Peggy T. Tinkey, D.V.M. The RASFH encompasses approximately 99,089 sq. ft. of space and provides housing, procedure space, veterinary care, and quality assurance programs for animals used in cancer research. Clinical, surgical, imaging, radiation therapy, and pathology laboratory facilities and services are provided. Existing technical services have been extended to the South Campus facility, and new services added since the last CCSG renewal include computerized animal pedigree and medical history applications, preclinical toxicology services, and increased transportation services. New equipment includes automated multi-species hematology and chemistry analyzers, patient monitoring systems, automated bedding dispensing systems and waste containers, cargo van, and 100 ventilated rodent rack/cage systems. The RASFH has 122 personnel, which includes 11 veterinarians, 2 associate directors, 1 administrator, 2 section managers, 1 project manager, 10 laboratory personnel, 77 animal care personnel, and 17 clerical/support staff. Dr. Tinkey coordinates the daily operations of the RASFH. Five faculty veterinarians direct the 5 service sections that provide facilities, equipment, and services to research animal users. Funding for the RASFH is currently provided by the CCSG (6%), user fees (39%), institutional support (53%) and other funds (2%). In the past 5 years, the RASFH has been used by 319 investigators supporting 20 different CCSG programs. Peer-reviewed investigators represent 92% of the RASFH user utilization. The majority of animals used are genetically engineered mice. In the past 5 years, the daily average cage counts increased 52%, from 13,243 cages in 2002-03 to 20,132 cages of animals in 2006-07. Future plans include renovation and expansion of the South Campus animal facility, and upgrading and implementing computer applications for business operations and preclinical drug development. Additionally, RASF-Houston and Smithville have jointly submitted a startup proposal to develop a Mutant Mouse Pathology Service to serve all MDACC investigators.

自最初的CCSG成立以来，研究动物支持设施（RASF）一直是一个共享资源