MT INBRE BIOINFORMATICS CORE

MT INBRE 生物信息学核心

• 批准号: 8359783
• 负责人: MICHAEL Roger FRANKLIN
• 金额: $ 17.06万
• 依托单位: MONTANA STATE UNIVERSITY - BOZEMAN
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8359783
• 关键词: Alaska; Bioinformatics; Biological; Centers of Research Excellence; Chemistry; Collaborations; Computational Biology; Core Facility; Data Base Management; Data Collection; Development; Educational process of instructing; Educational workshop; Electron Microscopy Facility; Faculty; Florida; Funding; Genomics; Goals; Grant; Informatics; Interdisciplinary Study; Mentors; Missouri; Montana; National Center for Research Resources; Principal Investigator; Proteomics; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resource Sharing; Resources; Services; Source; Students; System; Systems Biology; Techniques; Training; United States National Institutes of Health; Universities; Wisconsin; Wyoming; base; cost; database design; functional genomics; graduate student; mass spectrometer; research facility; success; tool; working group

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Directed by Drs. Michael Franklin and Jean Starkey and assisted by Informatics Coordinator Kate McInnerney, the MT INBRE Bioinformatics and Genomics Core provides investigators in the Research Core as well as faculty and students across the network and other states (Alaska, Wyoming, Wisconsin, Florida and Missouri) expertise in data collection, management, and analysis, in addition to expertise in proteomics, genomics, computational biology, and database design and management. Investigators and their students have access to and technical support for the Bioinformatics Core Facility (which includes the Bioinformatics Teaching and Research Facility and Systems Biology Computational Cluster), MSU's Proteomics and Biological Mass Spectrometer Facility, the Functional Genomics Core Facility, Environmental Chemistry Lab, and the University of Montana's Electron Microscopy Facility. The Bioinformatics and Genomics Core provides mentoring and training opportunities to Montana's researchers, including online courses in bioinformatics, data collection, management, and analysis, training in the tools and techniques commonly used in bioinformatics, and workshops for students and faculty. The resources and expertise contributed by the Core are integral to investigators and their students and facilitate the incorporation of bioinformatics analyses into research projects. Bioinformatics Core staff include, in addition to Drs. Franklin and Starkey and Ms. McInnerney, Dr. Aurelien Mazurie, Senior Bioinformatician; Gary Orser, Systems Administration; Joyce Brewer, Proteomics Analysis (graduate student); and Joanna Gress, graduate student in the Functional Genomics Core Facility. Building on successes in INBRE I, the Bioinformatics and Genomics Core focuses on strengthening the state's biomedical and bioinformatics infrastructure through continued development of shared facilities, research collaborations and mentoring, working groups, and training opportunities. The Core has 4 specific goals: 1) maintain and support the Bioinformatics Teaching and Research Lab and Systems Biology Computational Cluster, 2) offer foundational tutorials, workshops and courses that enable users to take advantage of bioinformatics tools and expose students to the expanding field of bioinformatics, 3) provide one-on-one technical support and mentoring of bioinformatics related research, and 4) collaborate with campus-based shared resource facilities, Montana INBRE and COBRE Project Leaders, regional INBRE bioinformatics cores, and other relevant groups to deliver services in an efficient and non-redundant manner.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 由博士执导。在 Michael Franklin 和 Jean Starkey 的信息协调员 Kate McInnerney 的协助下，MT INBRE 生物信息学和基因组学核心为研究核心的研究人员以及整个网络和其他州（阿拉斯加州、怀俄明州、威斯康星州、佛罗里达州和密苏里州）的教师和学生提供数据收集、管理和分析方面的专业知识，此外还提供蛋白质组学、基因组学、计算生物学、 以及数据库设计和管理。 研究人员及其学生可以使用生物信息学核心设施（包括生物信息学教学和研究设施以及系统生物学计算集群）、密歇根州立大学的蛋白质组学和生物质谱仪设施、功能基因组学核心设施、环境化学实验室和蒙大拿大学的电子显微镜设施并获得技术支持。 生物信息学和基因组学核心为蒙大拿州的研究人员提供指导和培训机会，包括生物信息学、数据收集、管理和分析的在线课程、生物信息学常用工具和技术的培训以及为学生和教师举办的研讨会。核心提供的资源和专业知识对于研究人员及其学生来说是不可或缺的，有助于将生物信息学分析纳入研究项目。 生物信息学核心人员除博士外还包括。 Franklin 和 Starkey 以及 McInnerney 女士、高级生物信息学家 Aurelien Mazurie 博士；加里·奥瑟，系统管理； Joyce Brewer，蛋白质组学分析（研究生）；乔安娜·格雷斯 (Joanna Gress)，功能基因组学核心设施的研究生。 以 INBRE I 的成功为基础，生物信息学和基因组学核心致力于通过持续开发共享设施、研究合作和指导、工作组和培训机会来加强该州的生物医学和生物信息学基础设施。 该核心有 4 个具体目标：1) 维护和支持生物信息学教学和研究实验室以及系统生物学计算集群，2) 提供基础教程、研讨会和课程，使用户能够利用生物信息学工具并使学生接触不断扩大的生物信息学领域，3) 提供生物信息学相关研究的一对一技术支持和指导，4) 与校园共享资源设施合作， 蒙大拿州 INBRE 和 COBRE 项目负责人、区域 INBRE 生物信息学核心以及其他相关团体以高效和非冗余的方式提供服务。