REU Site: Bioinformatics Research and Interdisciplinary Training Experience in Analysis and Interpretation of Information-Rich Biological Data Sets (REU-BRITE)

该REU Site奖授予位于马萨诸塞州波士顿的波士顿大学，将在2020-2022年夏季期间支持10名学生进行为期10周的培训。预计共有30名学生将在该方案中接受培训，这些学生主要来自研究机会有限的学校或代表性不足的群体。学生将学习研究是如何进行的，许多人将在科学会议上展示他们的工作成果。该计划将帮助培训一批未来的生物信息学科学家，他们了解并能够轻松操作广泛的计算、数学和统计技术，以分析和模拟当代生物实验产生的非常庞大的数据集。该计划的研究成果有望为生物研究创造新的基于知识的资源。将通过SALG Urssa在线工具对该方案进行评估。项目结束后将对学生进行跟踪，以确定他们的职业道路。该项目将重点放在对生物数据的计算和数学分析上。学生将与波士顿大学生物信息学教师导师一起在广泛的生物学研究领域中的一个领域进行全职研究，包括人类和环境中的微生物组、遗传变异和表型之间的联系、基因调控网络、生物分子相互作用和生态预测。学生将学习如何分析高通量数据，获得统计和机器学习方法方面的经验，并协助开发计算工具和方法。内容包括：1)生物信息学计算研讨会，2)创建科学摘要和海报的研讨会，3)本科生研究会议的海报展示，4)对社区中小学生的教育推广，5)波士顿大学生物信息学赞助的研讨会上的科学丰富和职业网络，6)准备竞争性研究生院申请的培训，7)科学伦理培训，以及8)波士顿地区的文化和社会丰富。参与者将由首席调查员和潜在的教师导师在完成在线申请后选择。有关该计划的更多信息，请访问http://sites.bu.edu/britereu/，或联系PI(gbenson@bu.edu)。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This REU Site award to Boston University, located in Boston, MA, will support the training of 10 students for 10 weeks during the summers of 2020- 2022. It is anticipated that a total of 30 students, primarily from schools with limited research opportunities or from an under-represented group, will be trained in the program. Students will learn how research is conducted, and many will present the results of their work at scientific conferences. The program will help train a diverse group of future bioinformatics scientists, who understand and can easily manipulate a wide range of computational, mathematical, and statistical techniques to analyze and model the very large data sets produced by contemporary biological experiments. Research outcomes from the program are expected to create new knowledge-based resources for biological research. Assessment of the program will be done through the online SALG URSSA tool. Students will be tracked after the program in order to determine their career paths.The program will focus on computational and mathematical analyses of biological data. Students will conduct full-time research with a Boston University Bioinformatics faculty mentor in one of a broad range of biological research fields, including the microbiome in humans and the environment, the linkage between genetic variation and phenotype, gene regulatory networks, biomolecular interactions, and ecological forecasting. Students will learn how to analyze high-throughput data, gain experience in statistical and machine learning methods, and assist with the development of computational tools and methodologies. Components will include: 1) workshops on bioinformatics computing, 2) workshops on creating a scientific abstract and poster, 3) poster presentation at an undergraduate research conference, 4) educational outreach to community elementary and middle school students, 5) scientific enrichment and career networking at Boston University Bioinformatics sponsored symposia, 6) training in preparing a competitive graduate school application, 7) training in scientific ethics, and 8) cultural and social enrichment in the Boston area. Participants will be selected by the Principal Investigator and potential faculty mentors after completion of an online application. More information about the program is available by visiting http://sites.bu.edu/britereu/, or by contacting the PI (Dr. Gary Benson at gbenson@bu.edu).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.