UAB Research and Education Program in Neurology, Neurosurgery, and Neuropathology

UAB 神经病学、神经外科和神经病理学研究和教育项目

• 批准号: 8331123
• 负责人: DAVID G. STANDAERT
• 金额: $ 6.19万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8331123
• 关键词: Address; Alabama; Award; Behavior; Clinical Research; Development; Discipline; Disease; Education; Educational process of instructing; Enrollment; Fellowship; Fostering; Future; Genetic; Genomics; Goals; Grant; Health; Human; Individual; Institution; K-Series Research Career Programs; Knowledge; Leadership; Mentors; Nervous System Physiology; Nervous system structure; Neurologic; Neurology; Neurosciences; Participant; Pathway interactions; Physicians; Positioning Attribute; Problem behavior; Public Health; Records; Research; Research Training; Residencies; Resources; Scientist; Societies; Staging; Structure; Synaptic plasticity; Time; Training; Universities; Writing; career; clinical practice; experience; nervous system disorder; neurochemistry; neurodevelopment; neuropathology; neurosurgery; programs; responsible research conduct; skills training

DESCRIPTION (provided by applicant): This is a proposal for a new R25 research education award at the University of Alabama at Birmingham (UAB). This program will support residents in neurology, neurosurgery, and neuropathology who are pursuing careers combining clinical practice and research, and foster their development as physician-scientists. Over the past two decades, considerable efforts and resources have been devoted to understanding nervous system function in health and disease, and the result has been a vast expansion of knowledge encompassing fundamental discoveries in genetics, genomics, neurochemistry, synaptic plasticity, neural development, and behavior. It is clear, however, that there is an important gap between these advances and applications to human health. There is a pressing need for physician-scientists trained to: i) integrate discoveries about the nervous system from several domains into multi-modal and multi-dimensional frameworks; and ii) formulate translational pathways to apply this knowledge to important biomedical and behavioral problems. The Program Director and Associate Director are both physician-scientists with established track records in research and training. Residents supported by this program will initiate their research during their residency training, and continue it into a period of research fellowship following residency. Participants from all three disciplines (neurology, neurosurgery and neuropathology) will engage in a total of two years in full time research training. Their research experience will e supported by a structured mentoring program along with didactic teaching in professional skills training, grant writing, and responsible conduct of research. The goal of the program will be to enable residents and fellows to develop a career in neurological research, and to prepare them to successfully compete for individual fellowships or mentored career development awards. As an institution, UAB is exceptionally well positioned to undertake research education in the neurosciences, and to develop the physician-scientists who will apply today's discoveries to solve the challenges of the future. PUBLIC HEALTH RELEVANCE: Narrative Diseases of the nervous system create a great burden on our citizens and society, and there is a critical need for new treatments and cures. This research education program will educate physician-scientists at the early stages of their training, and provide them with the knowledge needed to address these important public health problems.

描述(由申请者提供)：这是阿拉巴马大学伯明翰分校(UAB)设立新的R25研究教育奖的建议。这项计划将支持神经学、神经外科和神经病理学方面的住院医生，他们正在追求临床实践和研究相结合的职业生涯，并促进他们作为内科科学家的发展。在过去的二十年里，人们投入了大量的努力和资源来了解神经系统在健康和疾病中的功能，其结果是知识的巨大扩展，包括在遗传学、基因组学、神经化学、突触可塑性、神经发育和行为方面的基本发现。然而，很明显，这些进展与人类健康的应用之间存在着重要的差距。迫切需要经过培训的内科科学家：i)将几个领域关于神经系统的发现整合到多模式和多维框架中；ii)制定翻译路径，将这些知识应用于重要的生物医学和行为问题。方案主任和副主任都是内科科学家，在研究和培训方面都有既定的记录。由该计划支持的住院医师将在住院医师培训期间启动他们的研究，并在住院医师培训后继续进行研究奖学金。来自所有三个学科(神经学、神经外科和神经病理学)的参与者将总共参加为期两年的全日制研究培训。他们的研究经验将得到一个结构化的指导计划的支持，以及在专业技能培训、拨款撰写和负责任的研究行为方面的教学。该计划的目标将是使住院医生和研究员能够在神经学研究领域发展事业，并为他们成功竞争个人奖学金或指导职业发展奖做好准备。作为一家机构，UAB处于非常有利的地位，可以进行神经科学方面的研究教育，并培养将应用今天的发现来解决未来挑战的内科科学家。 公共卫生相关性：神经系统疾病给我们的公民和社会造成了巨大的负担，迫切需要新的治疗方法和疗法。这一研究教育计划将在培训的早期阶段教育内科科学家，并为他们提供解决这些重要公共卫生问题所需的知识。